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dc.contributorWichita State University. Department of Chemistryen_US
dc.contributor.authorDou, Dengfengen_US
dc.contributor.authorTiew, Kok-Chuanen_US
dc.contributor.authorHe, Guijiaen_US
dc.contributor.authorMandadapu, Sivakoteswara Raoen_US
dc.contributor.authorAravapalli, Sridharen_US
dc.contributor.authorAlliston, Kevin R.en_US
dc.contributor.authorKim, Yunjeongen_US
dc.contributor.authorChang, Kyeong-Oken_US
dc.contributor.authorGroutas, William C.en_US
dc.date.accessioned2012-02-06T17:16:06Z
dc.date.available2012-02-06T17:16:06Z
dc.date.issued2011-10-15en_US
dc.identifier21925886.0en_US
dc.identifier9413298en_US
dc.identifierS0968-0896(11)00688-2en_US
dc.identifierAI081891en_US
dc.identifier.citationBioorganic & medicinal chemistry. 2011 Oct 15; 19(20): 5975-83.en_US
dc.identifier.issn1464-3391en_US
dc.identifier.issn0968-0896en_US
dc.identifier.urihttp://dx.doi.org/10.1016/j.bmc.2011.08.054en_US
dc.identifier.urihttp://hdl.handle.net/10057/4307
dc.descriptionClick on the DOI link below to access the article (may not be free).en_US
dc.description.abstractA new class of compounds that exhibit anti-norovirus activity in a cell-based system and embody in their structure a cyclosulfamide scaffold has been identified. The structure of the initial hit (compound 2a, ED(50) 4 µM, TD(50) 50 µM) has been prospected by exploiting multiple points of diversity and generating appropriate structure-activity relationships.en_US
dc.description.sponsorshipNIAID NIH HHSen_US
dc.format.extent5975-83en_US
dc.language.isoengen_US
dc.publisherElsevieren_US
dc.relation.ispartofseriesBioorganic & medicinal chemistryen_US
dc.relation.ispartofseriesBioorg. Med. Chem.en_US
dc.sourceNLMen_US
dc.subjectResearch Support, N.I.H., Extramuralen_US
dc.titlePotent inhibition of Norwalk virus by cyclic sulfamide derivativesen_US
dc.typeArticleen_US
dc.coverage.spacialEnglanden_US
dc.description.versionpeer revieweden_US
dc.rights.holderCopyright © 2011, Elsevieren_US


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