Show simple item record

Inhibition of human leukocyte proteinase 3 by a novel recombinant serine proteinase inhibitor (LEX032)

dc.contributorWichita State University. Department of Chemistryen_US
dc.contributor.authorGroutas, William C.en_US
dc.contributor.authorRuan, Sumeien_US
dc.contributor.authorKuang, Rongzeen_US
dc.contributor.authorHook, Jerry B.en_US
dc.contributor.authorSands, Howarden_US
dc.date.accessioned2012-02-06T17:16:04Z
dc.date.available2012-02-06T17:16:04Z
dc.date.issued1997-04-28en_US
dc.identifier9168917en_US
dc.identifier0372516en_US
dc.identifierS0006-291X(97)96526-8en_US
dc.identifier.citationBiochemical and biophysical research communications. 1997 Apr 28; 233(3): 697-9.en_US
dc.identifier.issn0006-291Xen_US
dc.identifier.urihttp://dx.doi.org/10.1006/bbrc.1997.6526en_US
dc.identifier.urihttp://hdl.handle.net/10057/4301
dc.descriptionClick on the DOI link below to access the article (may not be free).en_US
dc.description.abstractThe interaction of a bioengineered serpin (LEX032) with human leukocyte proteinase 3 (PR 3) has been investigated. LEX032 was found to be a time-dependent inhibitor of PR 3, forming a highly-stable enzyme-inhibitor complex (Ki 12 nM).en_US
dc.format.extent697-9en_US
dc.language.isoengen_US
dc.publisherElsevieren_US
dc.relation.ispartofseriesBiochemical and biophysical research communicationsen_US
dc.relation.ispartofseriesBiochem. Biophys. Res. Commun.en_US
dc.sourceNLMen_US
dc.subjectIn Vitroen_US
dc.subjectResearch Support, Non-U.S. Gov'ten_US
dc.subject.meshAmino Acid Sequenceen_US
dc.subject.meshBinding Sites/geneticsen_US
dc.subject.meshHumansen_US
dc.subject.meshKineticsen_US
dc.subject.meshLeukocytes/enzymologyen_US
dc.subject.meshMyeloblastinen_US
dc.subject.meshRecombinant Proteins/geneticsen_US
dc.subject.meshSerine Endopeptidases/metabolismen_US
dc.subject.meshSerine Proteinase Inhibitors/geneticsen_US
dc.subject.meshSerpins/geneticsen_US
dc.subject.meshRecombinant Proteins/pharmacologyen_US
dc.subject.meshSerine Proteinase Inhibitors/pharmacologyen_US
dc.subject.meshSerpins/pharmacologyen_US
dc.titleInhibition of human leukocyte proteinase 3 by a novel recombinant serine proteinase inhibitor (LEX032)en_US
dc.typeArticleen_US
dc.coverage.spacialUnited Statesen_US
dc.description.versionpeer revieweden_US
dc.rights.holderCopyright © 1997, Elsevieren_US


Files in this item

FilesSizeFormatView

There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record