Evidence for a hydrogen abstraction mechanism in P450-catalyzed N-dealkylations
Bhakta, Mehul N.
Hollenberg, Paul F.
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Chemical communications (Cambridge, England). 2005 Jan 14; (2): 265-7.
The experimental evidence presented in this manuscript suggest against the widely accepted single electron/proton transfer mechanism for P450 catalyzed N-dealkylations and provides strong support for a hydrogen atom abstraction mechanism.
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