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dc.contributor.authorMontañez, Cindy S.en_US
dc.contributor.authorMcDonald, J. Daviden_US
dc.date.accessioned2012-01-24T17:49:37Z
dc.date.available2012-01-24T17:49:37Z
dc.date.issued1999-09en_US
dc.identifier10479487en_US
dc.identifier9805456en_US
dc.identifierS1096-7192(99)92887-1en_US
dc.identifier.citationMolecular genetics and metabolism. 1999 Sep; 68(1): 91-2.en_US
dc.identifier.issn1096-7192en_US
dc.identifier.urihttp://dx.doi.org/10.1006/mgme.1999.2887
dc.identifier.urihttp://hdl.handle.net/10057/4189
dc.descriptionClick on the DOI link below to access the article (may not be free).en_US
dc.description.abstractOur research establishes genetic linkage between the hph-1 mutation and the GTP-CH I structural gene. Our results indicate that these two loci are within an 8 cM region with 95% confidence. This finding lends additional support for the use of the hph-1 mouse mutant as a bona fide model system for the human disorder GTP-CH I to further our understanding of the molecular mechanisms involved in the disease pathology of GTP-CH I deficiency.en_US
dc.language.isoengen_US
dc.publisherAcademic Pressen_US
dc.relation.ispartofseriesMolecular genetics and metabolismen_US
dc.sourceNLMen_US
dc.subject.meshAllelesen_US
dc.subject.meshAnimalsen_US
dc.subject.meshCrosses, Geneticen_US
dc.subject.meshFemaleen_US
dc.subject.meshGTP Cyclohydrolase/deficiencyen_US
dc.subject.meshGenes/geneticsen_US
dc.subject.meshGenetic Linkageen_US
dc.subject.meshGenotypeen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshMiceen_US
dc.subject.meshMice, Inbred C57BLen_US
dc.subject.meshMice, Inbred CBAen_US
dc.subject.meshMice, Mutant Strainsen_US
dc.subject.meshMutationen_US
dc.subject.meshGTP Cyclohydrolase/geneticsen_US
dc.titleLinkage analysis of the hph-1 mutation and the GTP cyclohydrolase I structural geneen_US
dc.typeArticleen_US
dc.description.versionpeer revieweden_US
dc.rights.holderCopyright @ 1999 Academic Press.en_US


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