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    ENU mutagenesis in the mouse

    Date
    2004-02
    Author
    McDonald, J. David
    Beier, David R.
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    Citation
    Current protocols in human genetics / editorial board, Jonathan L. Haines ... [et al.]. 2004 Feb; Chapter 15: Unit 15.4.
    Abstract
    This unit describes the treatment of laboratory mice with the mutagen N-ethyl-N-nitrosourea (ENU) to achieve very highly induced rates of mutation throughout the genome. Further, it describes several popular mating schemes designed to produce animals displaying phenotypes associated with the induced mutations.
    Description
    Click on the DOI link below to access the article (may not be free).
    URI
    http://dx.doi.org/10.1002/0471142905.hg1504s39
    http://hdl.handle.net/10057/4168
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