ENU mutagenesis in the mouse
McDonald, J. David
Beier, David R.
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Current protocols in human genetics / editorial board, Jonathan L. Haines ... [et al.]. 2004 Feb; Chapter 15: Unit 15.4.
This unit describes the treatment of laboratory mice with the mutagen N-ethyl-N-nitrosourea (ENU) to achieve very highly induced rates of mutation throughout the genome. Further, it describes several popular mating schemes designed to produce animals displaying phenotypes associated with the induced mutations.
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