Browsing CHEM Faculty Publications by Subject "3c-like proteases"

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    • Oxadiazole-based cell permeable macrocyclic transition state inhibitors of norovirus 3CL protease 

      Damalanka, Vishnu C.; Kim, Yunjeong; Alliston, Kevin R.; Weerawarna, Pathum M.; Kankanamalage, Anushka C. Galasiti; Lushington, Gerald H.; Mehzabeen, Nurjahan; Battaile, Kevin P.; Lovell, Scott; Chang, Kyeong-Ok; Groutas, William C. (American Chemical Society, 2016-03-10)
      Human noroviruses are the primary causative agents of acute gastroenteritis and a pressing public health burden worldwide. There are currently no vaccines or small molecule therapeutics available for the treatment or ...