Browsing CHEM Faculty Scholarship by Type "Patent"
Now showing items 1-7 of 7
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1,2,5, thiadiazolidin-3-one 1,1-dioxide derivatives
(United States Patent and Trademark Office, 2002-07-16)Substituted derivatives of 1,2,5-thiadiazolidin-3-one 1,1-dioxides, oligomers containing them, and methods of using them. -
Broad-spectrum antivirals against 3C or 3C-like proteases of picornavirus-like supercluster: picornaviruses, caliciviruses and coronaviruses
(United States Patent and Trademark Office, 2016-10-25)Antiviral protease inhibitors, including peptidyl aldehydes, peptidyl .alpha.-ketoamides, peptidyl bisulfate salts, and peptidyl heterocycles, are disclosed, along with related antiviral compounds, and methods of using the ... -
Latent isocynate derivatives useful for deactivating enzymes
(United States Patent and Trademark Office, 1990-05-29)Certain amino-acid derivatives are disclosed as effective inhibitors of human leukocyte elastase and therefore useful in preventing the imbalance of this proteolytic enzyme in vivo. The compounds specifically are derivatives ... -
Macrocyclic and peptidomimetic compounds as broad-spectrum antivirals against 3C or 3C-like proteases of picornaviruses, caliciviruses and coronaviruses
(United States Patent and Trademark Office, 2016-04-12)Antiviral protease inhibitors, including macrocylic transition state inhibitors and peptidomimetics are disclosed, along with related antiviral compounds, and methods of using the same to treat or prevent viral infection ... -
Serine protease inhibitors
(United States Patent and Trademark Office, 1996-08-27)Isothiazolidin-3-one-1,1 dioxide, 3-oxo-1,2,5-thiadiazolidine-1,1,-dioxide and derivatives thereof, reduce or inhibit the activity of serine proteases. Such compounds are useful as anti-inflammatory and anti-metastatic agents. -
Sulfamide and bis-sulfamide amino acid derivatives as inhibitors of proteolytic enzymes
(United States Patent and Trademark Office, 2002-12-17)Compounds of the general formula I are provided: ##STR1## and pharmaceutically acceptable salts thereof, wherein, Z is a chemical species or R.sub.i capable of binding at a primary specificity site of a protease; Y is a ... -
Viral and fungal inhibitors
(United States Patent and Trademark Office, 2013-08-20)Novel classes of viral and fungal inhibitors are disclosed. These compounds are useful in treating, preventing, and/or ameliorating viral infections such as, for example, Hepatitis C Virus, West Nile Virus, Dengue Virus, ...