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    • Serine protease inhibitors 

      Groutas, William C. (United States Patent and Trademark Office, 1996-08-27)
      Isothiazolidin-3-one-1,1 dioxide, 3-oxo-1,2,5-thiadiazolidine-1,1,-dioxide and derivatives thereof, reduce or inhibit the activity of serine proteases. Such compounds are useful as anti-inflammatory and anti-metastatic agents.