Browsing CHEM Faculty Scholarship by Subject "Imidazolidines/pharmacology"
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Inhibitors of human neutrophil elastase based on a highly functionalized N-amino-4-imidazolidinone scaffold
(Elsevier, 2010-09-01)A series of compounds based on the N-amino-4-imidazolidinone scaffold was synthesized and screened against human neutrophil elastase (HNE). These studies lead to the identification of a selective, low micromolar reversible ...