Browsing CHEM Faculty Scholarship by Subject "Histidine/chemistry"
Now showing items 1-3 of 3
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Effect of 2-fluorohistidine labeling of the anthrax protective antigen on stability, pore formation, and translocation
(American Chemical Society, 2007-12-25)The action of anthrax toxin relies in part upon the ability of the protective antigen (PA) moiety to form a heptameric pore in the endosomal membrane, providing a portal for entry of the enzymic moieties of the toxin into ... -
Evidence that histidine protonation of receptor-bound anthrax protective antigen is a trigger for pore formation
(American Chemical Society, 2010-08-24)The protective antigen (PA) component of the anthrax toxin forms pores within the low pH environment of host endosomes through mechanisms that are poorly understood. It has been proposed that pore formation is dependent ... -
Gas-phase investigation of Pd(II)-alanine complexes with small native and derivatized peptides containing histidine
(John Wiley and Sons, 2003-09-01)We report here the generation of gas-phase complexes containing Pd(II), a ligand (deprotonated alanine, A-), and/or N-terminus derivatized peptides containing histidine as one of the amino acids. The species were produced ...