Browsing CHEM Faculty Scholarship by Subject "Genetic barrier"

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Characterization of amino acid substitutions in feline coronavirus 3C-like protease from a cat with feline infectious peritonitis treated with a protease inhibitor

Perera, Krishani Dinali; Rathnayake, Athri D.; Liu, Hongwei; Pedersen, Niels C.; Groutas, William C.; Chang, Kyeong-Ok; Kim, Yunjeong (Elsevier, 2019-10)

Feline infectious peritonitis (FIP) is a highly fatal disease caused by a virulent feline coronavirus in domestic and wild cats. We have previously reported the synthesis of potent coronavirus 3C-like protease (3CLpro) ...