Browsing CHEM Faculty Scholarship by Author "Schatz, E. J."
Groutas, William C.; Stanga, Michael A.; Castrisos, J.C.; Schatz, E. J. (Informa Healthcare, 1990-01-01)Derivatives of hydantoin have been found to inactivate human leukocyte elastase irreversibly. Chymotrypsin and cathepsin G are also inhibited by these compounds.
Inhibition of human leukocyte elastase by derivatives of N-hydroxysuccinimide. A structure-activity-relationship study Groutas, William C.; Brubaker, Michael J.; Stanga, Michael A.; Castrisos, J.C.; Crowley, J.P.; Schatz, E. J. (American Chemical Society, 1989-07-01)A series of compounds derived from 3-alkyl-N-hydroxysuccinimide have been synthesized and their inhibitory activity toward human leukocyte elastase has been investigated. Compounds having an isobutyl or isopropyl group at ...
Ionic inhibitors of human leukocyte elastase: pyridinium and phenyl carboxylate derivatives of 3-alkyl-N-hydroxysuccinimide Groutas, William C.; Stanga, Michael A.; Castrisos, J.C.; Schatz, E. J.; Brubaker, Michael J. (John Wiley and Sons, 1990-10-01)A series of pyridinium and phenyl carboxylate derivatives of 3-alkyl-N-hydroxysuccinimide has been synthesized; the compounds have been shown to be highly effective, time-dependent inactivators of human leukocyte elastase. ...