Browsing CHEM Faculty Scholarship by Author "Otey, Carol A."
Now showing items 1-4 of 4
-
Palladin and regulation of actin crosslinking and dynamics
Beck, Moriah R.; Dixon, Richard D.S.; Goicoechea, Silvia M.; Murphy, Grant S.; Otey, Carol A.; Campbell, Sharon L. (Wiley-Blackwell, 2012-08)Palladin is a recently discovered actin-associated protein that appears to be involved in both normal cell migration and invasive cell motility. Recently, we demonstrated that palladin is able to both bind and bundle actin ... -
Palladin Can Compensate for Arp2/3 Complex Defects and Structurally Organizes Actin-Rich Structures Generated during Listeria monocytogenes Infections
Dhanda, Aaron S.; Vogl, A. Wayne; Otey, Carol A.; Beck, Moriah R.; Guttman, Julian A. (Federation of American Societies for Experimental Biology, 2017-04)The actin cytoskeleton is co-opted by the invasive and motile bacteria Listeria monocytogenes (Listeria) for their entry, intracellular motility and dissemination from one cell to another. Once inside host cells, these ... -
Palladin compensates for the Arp2/3 complex and supports actin structures during Listeria Infections
Dhanda, Aaron S.; Vogl, A. Wayne; Albraiki, Sharifah E.; Otey, Carol A.; Beck, Moriah R.; Guttman, Julian A. (American Society For Microbiology, 2018-04-10)Palladin is an important component of motile actin-rich structures and nucleates branched actin filament arrays in vitro. Here we examine the role of palladin during Listeria monocytogenes infections in order to tease out ... -
Structure and function of palladin’s actin binding domain
Beck, Moriah R.; Dixon, Richard D.S.; Goicoechea, Silvia M.; Murphy, Grant S.; Brungardt, Joseph G.; Beam, Matthew T.; Srinath, Pavan; Patel, Julie; Mohiuddin, Jahan; Otey, Carol A.; Campbell, Sharon L. (Elsevier, 2013-06-25)Here we report the NMR structure of the actin-binding domain contained in the cell adhesion protein palladin. Previously we demonstrated that one of the immunoglobulin domains of palladin (Ig3) is both necessary and ...