Browsing CHEM Faculty Scholarship by Author "Gay-Andrieu, Francoise"

Now showing items 1-2 of 2

    • Amino acid-derived 1,2-benzisothiazolinone derivatives as novel small-molecule antifungal inhibitors: identification of potential genetic targets 

      Alex, Deepu; Gay-Andrieu, Francoise; May, Jared; Thampi, Linta; Dou, Dengfeng; Mooney, Aileen; Groutas, William C.; Calderone, Richard (American Society of Microbiology, 2012-09)
      We have identified four synthetic compounds (DFD-VI-15, BD-I-186, DFD-V-49, and DFD-V-66) from an amino acid-derived 1,2-benzisothiazolinone (BZT) scaffold that have reasonable MIC50 values against a panel of fungal ...

    • Antifungal drug discovery: the process and outcomes 

      Calderone, Richard; Sun, Nuo; Gay-Andrieu, Francoise; Groutas, William C.; Weerawarna, Pathum M.; Prasad, Sridhar; Alex, Deepu; Li, Dongmei (Future Medicine Ltd, 2014-06)
      New data suggest that the global incidence of several types of fungal diseases have traditionally been under- documented. Of these, mortality caused by invasive fungal infections remains disturbingly high, equal to or ...