Now showing items 1-2 of 2

    • Fast and effective ion mobility-mass spectrometry separation of D-amino-acid-containing peptides 

      Fouque, Kevin Jeanne Dit; Garabedian, Alyssa; Porter, Jacob; Baird, Matthew A.; Pang, Xueqin; Williams, Todd D.; Li, Lingjun; Shvartsburg, Alexandre A.; Fernandez-Lima, Francisco (American Chemical Society, 2017-11-01)
      Despite often minute concentrations in vivo, d-amino acid containing peptides (DAACPs) are crucial to many life processes. Standard proteomics protocols fail to detect them as d/l substitutions do not affect the peptide ...
    • Linear and differential ion mobility separations of middle-down proteoforms 

      Garabedian, Alyssa; Baird, Matthew A.; Porter, Jacob; Fouque, Kevin Jeanne Dit; Shliaha, Pavel V.; Jensen, Ole N.; Williams, Todd D.; Fernandez-Lima, Francisco; Shvartsburg, Alexandre A. (American Chemical Society, 2018)
      Comprehensive characterization of proteomes comprising the same proteins with distinct post-translational modifications (PTMs) is a staggering challenge. Many such proteoforms are isomers (localization variants) that require ...