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    • Structure-guided design of potent spirocyclic inhibitors of severe acute respiratory syndrome coronavirus-2 3C-like protease 

      Dampalla, Chamandi S.; Rathnayake, Athri D.; Galasiti Kankanamalage, Anushka C.; Kim, Yunjeong; Perera, Krishani Dinali; Nguyen, Harry Nhat; Miller, Matthew J.; Madden, Trent K.; Picard, Hunter R.; Thurman, Hayden A.; Kashipathy, Maithri M.; Liu, Lijun; Battaile, Kevin P.; Lovell, Scott; Chang, Kyeong-Ok; Groutas, William C. (American Chemical Society, 2022-06-09)
      The worldwide impact of the ongoing COVID-19 pandemic on public health has made imperative the discovery and development of direct-acting antivirals aimed at targeting viral and/or host targets. SARS-CoV-2 3C-like protease ...