Browsing CHEM Faculty Scholarship by Author "English, Douglas S."
Now showing items 1-7 of 7
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Controlling the role of oxygen in single molecule fluorescence measurements
English, Douglas S.; Campos, Luis A.; Wang, Zifan; Liu, Jianwei; Wang, Xiang; Ramanathan, Ravishankar; Munoz, Victor (American Chemical Society, 2011-08-28) -
Developing a targeting system for bacterial membranes: measuring receptor-phosphatidylglycerol interactions with H-1 NMR, ITC and fluorescence correlation spectroscopy
Alliband, Amanda M.; Wang, Zifan; Thacker, Christopher; English, Douglas S.; Burns, Dennis H. (Royal Society of Chemistry, 2015)An ammonium picket porphyrin that targets bacterial membranes has been prepared and shown to bind to phosphatidylglycerol (PG), a bacterial lipid, when the lipid was in solution, contained within synthetic membrane vesicles, ... -
Exploring one-state downhill protein folding in single molecules
Liu, Jianwei; Campos, Luis A.; Cerminara, Michele; Wang, Xiang; Ramanathan, Ravishankar; English, Douglas S.; Munoz, Victor (National Academy of Sciences, 2012-01-3)A one-state downhill protein folding process is barrierless at all conditions, resulting in gradual melting of native structure that permits resolving folding mechanisms step-by-step at atomic resolution. Experimental ... -
LacI-DNA-IPTG Loops: Equilibria among conformations by single-molecule FRET
Goodson, Kathy A.; Wang, Zifan; Haeusler, Aaron R.; Kahn, Jason D.; English, Douglas S. (American Chemical Society, 2013-02-13)The E. coli Lac repressor (LacI) tetramer binds simultaneously to a promoter-proximal DNA binding site (operator) and an auxiliary operator, resulting in a DNA loop, which increases repression efficiency. Induction of the ... -
Loading and release of doxorubicin with magnetic nanotubes
Bai, Xia; Wang, Xiang; English, Douglas S.; Lee, Sang Bok (John Wiley & Sons, Inc., 2015-03)In this work, we study magnetic nanotubes (MNTs) as drug carriers to control the loading and release of doxorubicin (Dox). The inner surfaces of MNTs where Dox molecules are stored are modified with C18-silane and ... -
The role of charge in the surfactant-assisted stabilization of the natural product curcumin
Wang, Zifan; Leung, Mandy H. M.; Kee, Tak W.; English, Douglas S. (American Chemical Society, 2010-04-20)Colloidal solutions of surfactants that form micelles or vesicles are useful for solubilizing and stabilizing hydrophobic molecules that are otherwise sparingly soluble in aqueous solutions. In this paper we investigate ... -
Synthesis, characterization, and application of antibody functionalized fluorescent silica nanoparticles
Hurley, Matthew T.; Wang, Zifan; Mahle, Amanda; Rabin, Daniel; Liu, Qing; English, Douglas S.; Zachariah, Michael R.; Stein, Daniel; DeShong, Philip (Wiley-V C H Verlag GMBH, 2013-07-12)Fluorescent silica nanoparticles (FSNs) are prepared by incorporating dye into a mesoporous silica nanoparticle (MSN) synthesis procedure. FSNs containing sulforhodamine B, hydrophobically modified sulforhodamine B, and ...