Browsing CHEM Faculty Scholarship by Author "Eichhorn, David M."
Now showing items 1-20 of 24
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2-Fluoro-l-histidine
Andra, Kiran K.; Bullinger, John C.; Bann, James G.; Eichhorn, David M. (International Union of Crystallography, 2010-01-01)The title compound, C(6)H(8)FN(3)O(2), an analog of histidine, shows a reduced side-chain pK(a) (ca 1). The title structure exhibits a shortening of the bond between the proximal ring N atom and the F-substituted ring C ... -
Cyanoscorpionate ligands: agostic interactions in a series of metal complexes containing the Tris(4-cyano-3-phenylpyrazolyl)borate and Bis(4-cyano-3-phenylpyrazolyl)borate ligands
Kadel, Lava R.; Bullinger, John R.; Baum, Robert R.; Moore, Curtis E.; Tierney, David L.; Eichhorn, David M. (Wiley Periodicals, Inc., 2016-06)Scorpionate chemistry has long featured sandwich complexes with two trispyrazolylborate (Tp) or two bispyrazolylborate (Bp) ligands coordinated to a transition metal. Less common are complexes in which one Tp and one Bp ... -
Cyanoscorpionates: synthesis and crystallographic characterization of one-dimensional Cu(I) coordination polymers
Zhao, Ningfeng; Bullinger, John C.; Van Stipdonk, Michael J.; Stern, Charlotte L.; Eichhorn, David M. (American Chemical Society, 2008-07-07)A new cyanoscorpionate ligand, hydrotris(3- t-butyl-4-cyanopyrazolyl)borate (Tp ( t-Bu,4CN )) is reported. Both Tp ( t-Bu,4CN ) and hydrotris(4-cyano-3-phenylpyrazolyl)borate (Tp (Ph,4CN)) form one-dimensional coordination ... -
Derivatized mixed-ring heterocyclic and antenna carotene ligands
Komreddy, Venugopal R.; Rillema, D. Paul; Nguyen, Huy A.; Cruz, Arvin; Moore, Curtis E.; Senaratne, Nilmini; Kadel, Lava R.; Eichhorn, David M. (American Chemical Society, 2018)General synthetic methods have been devised to prep. derivatized mixed-ring heterocyclic and antenna carotene ligands with nitrogen donor atoms. Synthetic methods involve prepn. of intermediate compds. in route to arom. ... -
Design, synthesis and characterization of novel 1,2-benzisothiazol-3(2H)-one and 1,3,4-oxadiazole hybrid derivatives: Potent inhibitors of Dengue and West Nile virus NS2B/NS3 proteases
Lai, Huiguo; Dou, Dengfeng; Aravapalli, Sridhar; Teramoto, Tadahisa; Lushington, Gerald H.; Mwania, Tom M.; Alliston, Kevin R.; Eichhorn, David M.; Padmanabhan, Radhakrishnan; Groutas, William C. (PERGAMON-ELSEVIER SCIENCE LTD, 2013-01)1,2-Benzisothiazol-3(2H)-ones and 1,3,4-oxadiazoles individually have recently attracted considerable interest in drug discovery, including as antibacterial and antifungal agents. In this study, a series of functionalized ... -
Dihydrobis(4-cyano-3-phenylpyrazol-1-yl)borate: homoleptic mononuclear cobalt(II) and copper(II) complexes with a cyano-substituted scorpionate ligand
Siemer, Christopher J.; Goswami, Niranjan; Kahol, Pawan K.; Van Stipdonk, Michael J.; Eichhorn, David M. (American Chemical Society, 2001-07-30) -
Incorporation of thiolate donation using 2,2'-dithiodibenzaldehyde: complexes of a pentadentate N2S3 ligand with relevance to the active site of Co nitrile hydratase
Smucker, Bradley W.; Van Stipdonk, Michael J.; Eichhorn, David M. (Elsevier, 2007-10-01)The use of 2,2'-dithiodibenzaldehyde (DTDB) as a reactant for incorporating thiolate donors into the coordination sphere of a transition metal complex without the need for protecting groups is expanded to include the ... -
Introducing supramolecular interactions into robust bis(tetrabromocatecholate) chelated manganese(III) systems and biomimetic catalytic activity
Panja, Anangamohan; Jana, Narayan Ch.; Bauza, Antonio; Adak, Sarmistha; Mwania, Tom M.; Eichhorn, David M.; Frontera, Antonio (John Wiley & Sons, Inc., 2017-02-23)This report deals with the syntheses, structures, supramolecular interactions, and biomimetic catalytic activity of three new manganese(III) complexes (1-3) containing the tetrabromocatechol ligand. Three different amines ... -
Iron and cobalt complexes of 2,6-Diacetylpyridine-bis(R-thiosemicarbazone) (R=H, phenyl) showing unprecedented ligand deviation from planarity
Panja, Anangamohan; Campana, Charles; Leavitt, Christopher M.; Van Stipdonk, Michael J.; Eichhorn, David M. (Elsevier, 2009-03-02)The syntheses, characterization, and single-crystal X-ray crystal structures are reported for four complexes of iron and cobalt with the pentadentate ligands, 2,6-diacetylpyridinebis(thiosemicarbazone) (H(2)L(1)) and ... -
A linear S-bridged trinuclear cobalt(III) complex with 2-aminobenzenethiol: synthesis, crystal structure, and spectroscopic characterization
Panja, Anangamohan; Moore, Curtis E.; Eichhorn, David M. (Taylor & Francis, 2013-09-10)Treatment of cobalt(II) perchlorate hexahydrate with 2 M equiv. of 2-aminobenzenethiol (Habt) in acetonitrile afforded a tricationic tricobalt complex, [Co{Co(abt)3}2](ClO4)3·2CH3CN, by aerial oxidation. The molecular ... -
Mono- and di-nuclear nickel(II) complexes with mixed N/S-donor ligands: Syntheses, structures and physical properties
Panja, Anangamohan; Eichhorn, David M. (Elsevier, 2012-05-03)Two new Ni(II) complexes are reported with tridentate thiosemicarbazone ligands derived from Schiff-base condensation with phenylthiosemicarbazide. Complex 1, a novel dinuclear Ni(II) complex of a SNS ligand synthesized ... -
New trisubstituted cyanopyrazoles and cyanoscorpionates
Kadel, Lava R.; Kromer, John R.; Moore, Curtis E.; Eichhorn, David M. (Elsevier B.V., 2017-03-29)New syntheses are reported to give pyrazoles with cyano substituents at the 4-position of the pyrazole ring and ethyl or isopropyl substituents at the 3-position, as well as pyrazoles with cyano substituents at the 4-position ... -
Ni complexes of N2S ligands with amine/imine and amine/amide donors with relevance to the active site of Ni superoxide dismutase
Senaratne, Nilmini K.; Mwania, Tom M.; Moore, Curtis E.; Eichhorn, David M. (Elsevier, 2018-05-01)A series of Ni complexes of the form [Ni((NNS)-S-Im)(RS)] ((NNS)-S-Im = (2-(N-(dimethylaminoethyl)iminomethyl) benzenethiolate; R = phenyl, 4-nitrophenyl, 4-fluorophenyl, 4-chlorophenyl, 4-t-butylphenyl, t-butyl), as well ... -
Sandwich compounds of cyanotrispyrazolylborates: complexation-induced ligand isomerization
Zhao, Ningfeng; Van Stipdonk, Michael J.; Bauer, Cary; Campana, Charles; Eichhorn, David M. (American Chemical Society, 2007-10-15)Reaction of the new cyanoscorpionate ligand, hydrotris(4-cyano-3-phenyl)pyrazolylborate (Tp(Ph),(4CN)) with Co(II), Mn(II), and Fe(II) unexpectedly results in the isolation only of crystals containing sandwich complexes ... -
Serendipitous discovery of an unexpected rearrangement leads to two new classes of potential protease inhibitors
Zhong, Jiaying; Lai, Zhong; Groutas, Christopher S.; Wong, Tzutshin; Gan, Xiangdong; Alliston, Kevin R.; Eichhorn, David M.; Hoidal, John R.; Groutas, William C. (Elsevier, 2004-12-01)The pathogenesis of a range of human diseases arises from the aberrant activity of proteolytic enzymes. Agents capable of selectively modulating the activity of these enzymes are of potential therapeutic value. Thus, there ... -
Structure, physical, and photophysical properties of platinum(II) complexes containing bidentate aromatic and bis(diphenylphosphino)methane as ligands
DePriest, Jeff; Zheng, Greg Y.; Goswami, Niranjan; Eichhorn, David M.; Woods, Clifton; Rillema, D. Paul (American Chemical Society, 2000-05-01)This study focuses on a series of PtII(L-L')(dppm)n+ complexes, where dppm is bis(diphenylphosphino)methane and L-L' are C-C' (n = 0), C-N (n = 1), and N-N' (n = 2) aromatic ligands. Structural characteristics are as ... -
Synthesis and luminescence properties of a nonsymmetrical ligand-bridged reI−reI chromophore
Xue, W. M.; Goswami, Niranjan; Eichhorn, David M.; Orizondo, Peter L.; Rillema, D. Paul (ACS Publications, 2000-09-15)The preparation and the physical and photophysical properties of three complexes containing the bridging ligand 5-(2-(4-pyridyl)ethyl)-2-(2-pyridyl)pyrimidine (pypm-py) are described. Two of the complexes are monometallic, ... -
Synthesis and x-ray crystallographic characterization of [In(tsalen)(OAc)] (tsalen = N,N '-ethylenebis(thiosalicylideneimine))
Sullivan, Michael T.; Senaratne, Nilmini K.; Eichhorn, David M. (Elsevier Science Inc., 2016-08-16)The first synthesis and crystallographic characterization of a main-group metal complex of the N2S2 ligand N,N'-ethylenebis(thiosalicylideneimine) (tsalen) is reported, with the isolation and characterization of the ... -
Synthesis, modification, and characterization of a family of homologues of exo-calix
Burns, Dennis H.; Chan, Ho-Kit; Miller, Jeffrey D.; Jayne, Charles L.; Eichhorn, David M. (American Chemical Society, 2000-08-25)A general strategy for the preparation of the family of exo-[n.m.n.m]metacyclophanes (n,m > or = 3) in 6-steps (starting from 2-bromoanisole) that utilizes a [2 + 2] approach to furnish the exo-metacyclophane ring in good ... -
Thallium(I) complexes of cyano-substituted bispyrazolylborate ligands
Johnson, Donald M.; Eichhorn, David M.; Moore, Curtis E.; Mwania, Tom M.; Zhao, Ningfeng (Springer, 2012-07)Two thallium scorpionate complexes: dihydrobis(3-phenyl-4-cyanopyrazolyl)boratothallium(I) (TlBp(Ph,4CN)), C20H14BN6Tl and dihydrobis(3-tert-butyl-4-cyanopyrazolyl)boratothallium(I) (TlBp (t-Bu,4CN)), C16H22BN6Tl have been ...