Browsing CHEM Faculty Scholarship by Author "Cardinale, Steven C."

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    • Design, synthesis, and evaluation of novel prodrugs of transition state inhibitors of norovirus 3CL protease 

      Kankanamalage, Anushka C. Galasiti; Kim, Yunjeong; Rathnayake, Athri D.; Alliston, Kevin R.; Butler, Michelle M.; Cardinale, Steven C.; Bowlin, Terry L.; Groutas, William C.; Chang, Kyeong-Ok (American Chemical Society, 2017-07-03)
      Ester and carbamate prodrugs of aldehyde bisulfite adduct inhibitors were synthesized in order to improve their pharmacokinetic and pharmacodynamic properties. The inhibitory activity of the compounds against norovirus ...