Browsing CHEM Faculty Scholarship by Author "Campbell, Sharon L."
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Palladin and regulation of actin crosslinking and dynamics
Beck, Moriah R.; Dixon, Richard D.S.; Goicoechea, Silvia M.; Murphy, Grant S.; Otey, Carol A.; Campbell, Sharon L. (Wiley-Blackwell, 2012-08)Palladin is a recently discovered actin-associated protein that appears to be involved in both normal cell migration and invasive cell motility. Recently, we demonstrated that palladin is able to both bind and bundle actin ... -
Protein-protein interaction analysis by nuclear magnetic resonance spectroscopy
Thompson, Peter M.; Beck, Moriah R.; Campbell, Sharon L. (Springer New York, 2015)Nuclear magnetic resonance (NMR) has continued to evolve as a powerful method, with an increase in the number of pulse sequences and techniques available to study protein-protein interactions. In this chapter, a straightforward ... -
Structure and function of palladin’s actin binding domain
Beck, Moriah R.; Dixon, Richard D.S.; Goicoechea, Silvia M.; Murphy, Grant S.; Brungardt, Joseph G.; Beam, Matthew T.; Srinath, Pavan; Patel, Julie; Mohiuddin, Jahan; Otey, Carol A.; Campbell, Sharon L. (Elsevier, 2013-06-25)Here we report the NMR structure of the actin-binding domain contained in the cell adhesion protein palladin. Previously we demonstrated that one of the immunoglobulin domains of palladin (Ig3) is both necessary and ...