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    • Discovery of a Redox-activatable chemical probe for detection of cyclooxygenase-2 in cells and animals 

      Uddin, Md. Jashim; Lo, Justin Han-Je; Oltman, Connor G.; Crews, Brenda C.; Huda, Tamanna; Liu, Justin; Kingsley, Philip J.; Lin, Shuyang; Milad, Mathew; Aleem, Ansari M.; Asaduzzaman, Abu; McIntyre, J. Oliver; Duvall, Craig L.; Marnett, Lawrence J. (American Chemical Society, 2022-07-15)
      Cyclooxygenase-2 (COX-2) expression is up-regulated in inflammatory tissues and many premalignant and malignant tumors. Assessment of COX-2 protein in vivo, therefore, promises to be a powerful strategy to distinguish ...