Browsing CHEM Faculty Scholarship by Title
Now showing items 308-327 of 491
-
P(450)/NADPH/O(2)- and P(450)/PhIO-catalyzed N-dealkylations are mechanistically distinct
(American Chemical Society, 2005-02-09)A high-valent iron-oxo species analogous to the compound I of peroxidases has been thought to be the activated oxygen species in P450-catalyzed reactions. Spectroscopic characterization of the catalytically competent ... -
Palladin and regulation of actin crosslinking and dynamics
(Wiley-Blackwell, 2012-08)Palladin is a recently discovered actin-associated protein that appears to be involved in both normal cell migration and invasive cell motility. Recently, we demonstrated that palladin is able to both bind and bundle actin ... -
Palladin Can Compensate for Arp2/3 Complex Defects and Structurally Organizes Actin-Rich Structures Generated during Listeria monocytogenes Infections
(Federation of American Societies for Experimental Biology, 2017-04)The actin cytoskeleton is co-opted by the invasive and motile bacteria Listeria monocytogenes (Listeria) for their entry, intracellular motility and dissemination from one cell to another. Once inside host cells, these ... -
Palladin compensates for the Arp2/3 complex and supports actin structures during Listeria Infections
(American Society For Microbiology, 2018-04-10)Palladin is an important component of motile actin-rich structures and nucleates branched actin filament arrays in vitro. Here we examine the role of palladin during Listeria monocytogenes infections in order to tease out ... -
Palladin Nucleates Actin Assembly and Regulates Cytoskeleton Architecture
(Elsevier Inc., 2015-01-27)The actin scaffold protein palladin regulates both normal cell migration and invasive cell motility, processes that require the coordinated regulation of actin dynamics. Palladin localizes to actin-rich protrusions and has ... -
Palladin's Ig4 Mutation: Exploring the link with pancreatic cancer
(Elsevier Inc., 2015-01-27)Palladin is a recently discovered protein that is expressed in human cells and plays a key role in cytoskeletal dynamics by directly binding and bundling filaments of actin. These processes provide an important function ... -
Periplasmic peptidyl prolyl cis-trans isomerases are not essential for viability, but SurA is required for pilus biogenesis in Escherichia coli
(American Society for Microbiology, 2005-08-31)In Escherichia coli, FkpA, PpiA, PpiD, and SurA are the four known periplasmic cis-trans prolyl isomerases. These isomerases facilitate proper protein folding by increasing the rate of transition of proline residues between ... -
Perturbation of dopamine metabolism by 3-amino-2-(4'-halophenyl)propenes leads to increased oxidative stress and apoptotic SH-SY5Y cell death
(American Society for Pharmacology and Experimental Therapeutics, 2007-09-01)We have recently characterized a series of 3-amino-2-phenyl-propene (APP) derivatives as reversible inhibitors for the bovine adrenal chromaffin granule vesicular monoamine transporter (VMAT) that have been previously ... -
pH effects on binding between the anthrax protective antigen and the host cellular receptor CMG2
(Wiley-Blackwell, 2012-10)The anthrax protective antigen (PA) binds to the host cellular receptor capillary morphogenesis protein 2 (CMG2) with high affinity. To gain a better understanding of how pH may affect binding to the receptor, we have ... -
pH-induced alteration and oxidative destruction of heme in purified chromaffin granule cytochrome b(561): implications for the oxidative stress in catecholaminergic neurons
(American Chemical Society, 2003-04-01)The transmembrane hemoprotein, cytochrome b(561) (b(561)), in the neuroendocrine secretory vesicles is shown to shuttle electrons from the cytosolic ascorbate (Asc) to the intravesicular matrix to provide reducing equivalents ... -
Phosphoinositide binding inhibits actin crosslinking and polymerization by palladin
(Elsevier B.V., 2016-10-09)Actin cytoskeleton remodeling requires the coordinated action of a large number of actin binding proteins that reorganize the actin cytoskeleton by promoting polymerization, stabilizing filaments, causing branching, or ... -
Photocatalytic conversion of CO2 to CO and acrylic acid
(American Chemical Society, 2014-03-16)The synthesis of various rhenium complexes was followed by an investigation of their capacity to reduce CO2 photocatalytically to CO. Re(bpy)(CO)3X (X = Cl, NCS; bpy = 2,2'-bipyridine) was irradiated in a CO2 saturated ... -
Photocatalytic reduction of CO2 to CO, and its study in the production of an organic acid
(American Chemical Society, 2013-04-07)The quantum efficiency to reduce of CO2 to CO photocatalytically using visible light will be described. Irradiation of saturated CO2 solutions of dimethylformide:triethanolamine (DMF:TEOA) containing two different dyes are ... -
Photochemical and photophysical properties of ruthenium(II) bis-bipyridine bis-nitrile complexes: Photolability
(Elsevier, 2010-08-10)The electrochemical and photophysical properties of two bis-nitrilo ruthenium(II) complexes formulated as [Ru(bpy)2(L)2](PF6)2, where bpy is 2,2′-bipyridine and L is AN = CH3CN and sn = NC–CH2CH2–CN, have been investigated. ... -
Photochemical charge separation in closely positioned donor-boron dipyrrin-fullerene triads
(John Wiley and Sons, 2011-02-14)A series of molecular triads, composed of closely positioned boron dipyrrin-fullerene units, covalently linked to either an electron donor (donor(1) -acceptor(1) -acceptor(2) -type triads) or an energy donor (antenna-donor(1) ... -
Photochemical charge separation in supramolecular phthalocyanine-multifullerene conjugates assembled by crown ether-alkyl ammonium cation interactions
(American Chemical Society, 2010-10-21)Self-assembled phthalocyanine-multifullerene donor-acceptor conjugates have been formed by crown ether-ammonium cation dipole-ion binding strategy to probe the photochemical charge separation. To achieve this, phthalocyanine ... -
Photochemistry and photophysics of coordination compounds: rhenium
(Springer Berlin Heidelberg, 2007)This review describes recent advances in the photochemistry of complexes of the element rhenium. It covers not only fundamental chemistry but the recent applications of these complexes to supramolecular chemistry, carbon ... -
Photoinduced charge separation in three-layer supramolecular nanohybrids: fullerene-porphyrin-SWCNT
(Royal Society of Chemistry, 2012-12-14)Photoinduced charge separation processes of three-layer supramolecular hybrids, fullerene-porphyrin-SWCNT, which are constructed from semiconducting (7,6)- and (6,5)-enriched SWCNTs and self-assembled via pi-pi interacting ... -
Photoinduced electron transfer in a Watson-Crick base-paired, 2-aminopurine:uracil-C60 hydrogen bonding conjugate
(Royal Society of Chemistry, 2007-02-07)A fluorescent reporter molecule, 2-aminopurine was self-assembled via Watson-Crick base-pairing to a uracil appended fullerene to form a donor-acceptor conjugate; efficient photoinduced charge separation was confirmed by ... -
Photophysical, spectroscopic, and computational studies of a series of Re(I) tricarbonyl complexes containing 2,6-dimethylphenylisocyanide and 5- and 6-derivatized phenanthroline ligands
(American Chemical Society, 2005-04-04)The ligand 2,6-dimethylphenylisocyanide (CNx) forms six complexes of the formula [Re(CO)3(CNx)(L)]+, where L = 1,10-phenanthroline (1), 5-chloro-1,10-phenanthroline (2), 5-nitro-1,10-phenanthroline (3), 5-methyl-1,10-phe ...