Browsing CHEM Faculty Scholarship by Title
Now showing items 39-58 of 491
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Ba$_6$(Cu$_x$Z$_y$)Sn$_4$S$_{16}$(Z = Mg, Mn, Zn, Cd, In, Bi, Sn): High chemical flexibility resulting in good nonlinear-optical properties
(American Chemical Society, 2022-02-07)Seven acentric sulfides Ba$_6$(Cu$_x$Z$_y$)Sn$_4$S$_{16}$ (Z = Mg, Mn, Zn, Cd, In, Bi, Sn) were grown by a high-temperature salt flux method. The crystal structures of the Ba$_6$(Cu$_x$Z$_y$)Sn$_4$S$_{16}$ (Z = Mg, Mn, Zn, ... -
Binding of the von Willebrand factor A domain of capillary morphogenesis protein 2 to anthrax protective antigen vaccine reduces immunogenicity in mice
(NLM (Medline), 2020-01)Protective antigen (PA) is a component of anthrax toxin that can elicit toxin-neutralizing antibody responses. PA is also the major antigen in the current vaccine to prevent anthrax, but stability problems with recombinant ... -
Binding sites of a positron emission tomography imaging agent in Alzheimer’s β amyloid fibrils studied using 19f solid-state NMR
(ACS Publications, 2022-01-11)Amyloid imaging by positron emission tomography (PET) is an important method for diagnosing neurodegenerative disorders such as Alzheimer’s disease. Many 11C- and 18F-labeled PET tracers show varying binding capacities, ... -
Binding, electrochemical activation, and cleavage of DNA by cobalt(II) tetrakis-N-methylpyridyl porphyrin and its beta-pyrrole brominated derivative
(American Chemical Society, 2006-11-01)The binding of nucleic acids by water-soluble cobalt(II) tetrakis-N-methylpyridyl porphyrin, (TMPyP)Co, and its highly electron-deficient derivative cobalt(II) tetrakis-N-methyl pyridyl-beta-octabromoporphyrin, (Br(8)TMPyP)Co, ... -
Bionano donor-acceptor hybrids of porphyrin, ssDNA, and semiconductive single-wall carbon nanotubes for electron transfer via porphyrin excitation
(American Chemical Society, 2011-12)Photoinduced electron transfer in self-assemblies of porphyrins ion-paired with ssDNA wrapped around single-wall carbon nanotubes (SWCNTs) has been reported. To accomplish the three-component hybrids, two kinds of ... -
Biophysical characterization and immunization studies of dominant negative inhibitor (DNI), a candidate anthrax toxin subunit vaccine
(Landes Bioscience, 2013-11)Dominant negative inhibitor (DNI) is a translocation-deficient homolog of recombinant protective antigen of Bacillus anthracis that is a candidate for a next generation anthrax vaccine. This study demonstrates that the ... -
The biophysical probes 2-fluorohistidine and 4-fluorohistidine: spectroscopic signatures and molecular properties
(Nature Publishing Group, 2017-02-15)Fluorinated amino acids serve as valuable biological probes, by reporting on local protein structure and dynamics through F-19 NMR chemical shifts. 2-fluorohistidine and 4-fluorohistidine, studied here with DFT methods, ... -
Biosynthetic incorporation of fluorohistidine into proteins in E. coli: a new probe of macromolecular structure
(John Wiley and Sons, 2005-12-01) -
Bis-functionalized fullerene-dibenzo[18]crown-6 conjugate: synthesis and cation-complexation dependent redox behavior
(Royal Society of Chemistry, 2003-07-21)A one-step synthesis of bis-pyrrolidine functionalized fullerene-dibenzo[18]crown-6 conjugate and its metal cation complexation to the crown ether entity dependent redox behavior is reported. -
Bisdonor-azaBODIPY-fullerene supramolecules: syntheses, characterization, and light-Induced electron-transfer studies
(American Chemical Society, 2014-02-06)Achieving ultrafast light-induced charge separation requires carefully selected donor and acceptor entities often held together in a closer proximity. In the present investigation, two tetrads featuring a near-IR-emitting ... -
A Bloembergen-Purcell-Pound 13C NMR relaxation study of the ionic liquid 1-butyl-3-methylimidazolium hexafluorophosphate
(Springer, 2004-03-01)The molecular structure and rotational motion of the ionic liquid 1-butyl-3-methylimidazolium hexafluorophosphate ([BMIM][PF6]) were studied over a wide temperature range using the Bloembergen-Purcell-Pound 13C NMR ... -
Borate complexes of benzohydroxamic acid and some of its derivatives
(Elsevier, 1966-07-01)Ultraviolet spectrophotometric measurements in dilute aqueous solution give pK(a) values of 8.78, 8.27, 8.96 and 8.68, respectively, for benzohydroxamic, N-phenylbenzohydroxamic, p-methoxybenzohydroxamic and N-methyl-p-m ... -
Boronate affinity chromatography
(Springer, 1992-01-01) -
Broad separation of isomeric lipids by high-resolution differential ion mobility spectrometry with tandem mass spectrometry
(Springer, 2017-08)Maturation of metabolomics has brought a deeper appreciation for the importance of isomeric identity of lipids to their biological role, mirroring that for proteoforms in proteomics. However, full characterization of the ... -
Broad-spectrum antivirals against 3C or 3C-like proteases of picornavirus-like supercluster: picornaviruses, caliciviruses and coronaviruses
(United States Patent and Trademark Office, 2016-10-25)Antiviral protease inhibitors, including peptidyl aldehydes, peptidyl .alpha.-ketoamides, peptidyl bisulfate salts, and peptidyl heterocycles, are disclosed, along with related antiviral compounds, and methods of using the ... -
Broad-spectrum antivirals against 3C or 3C-like proteases of picornaviruses, noroviruses, and coronaviruses
(American Society of Microbiology, 2012-08-22)Phylogenetic analysis has demonstrated that some positive-sense RNA viruses can be classified into the picornavirus-like supercluster, which includes picornaviruses, caliciviruses, and coronaviruses. These viruses possess ... -
Broad-spectrum cyclopropane-based inhibitors of coronavirus 3C-like proteases: Biochemical, structural, and virological studies
(American Chemical Society, 2022-12-28)The advent of SARS-CoV-2, the causative agent of COVID-19, and its worldwide impact on global health, have provided the impetus for the development of effective countermeasures that can be deployed against the virus, ... -
Broad-spectrum inhibitors against 3C-like proteases of feline coronaviruses and feline caliciviruses
(American Society for Microbiology, 2015-05)Feline infectious peritonitis and virulent, systemic calicivirus infection are caused by certain types of feline coronaviruses (FCoVs) and feline caliciviruses (FCVs), respectively, and are important infectious diseases ... -
Buried solvent determines both anion-binding selectivity and binding stoichiometry with hydrogen-bonding receptors
(American Chemical Society, 2005-04-01)The crystal structure of a tetraurea picket porphyrin-chloride anion complex has previously shown the anion to be situated between two adjacent ureas and hydrogen bonded via four NH protons (J. Am. Chem. Soc. 1998, 120, ... -
Caenorhabditis elegans model studies show $MPP^+$is a simple member of a large group of related potent dopaminergic toxins
(American Chemical Society, 2021-01-26)Although the causes of Parkinson’s disease (PD) are not fully understood, the consensus is that a combination of genetic and environmental factors plays a major role. The discovery that the synthetic chemical, 1-methyl-4 ...