Browsing BIO Theses by Author "Bousfield, George R."
Now showing items 1-6 of 6
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Analysis of oligosaccharyltransferase isoform function in human follicle stimulating hormone via siRNA knockdown
Chambers, Carrie Anne (Wichita State University, 2013-12)Follicle-stimulating hormone (FSH) is a glycoprotein hormone with two subunits, alpha and beta, and is required for gamete development. FSH is now known to exist as a ratio of two glycoforms that varies during the menstrual ... -
Expression of a novel follicle stimulating hormone glycoform
Tran, Thao P. (Wichita State University, 2010-05)Heterodimeric pituitary gonadotropins, luteinizing hormone (LH) and follicle-stimulating hormone (FSH), play significant roles in follicular development and maintenance of the female reproductive cycle. FSH functions in ... -
Follicle-stimulating hormone glycoform interactions with the FSH receptor
Elsaid, Ramy (Wichita State University, 2015-07)Follicle-stimulating hormone (FSH) is a gonadotropic hormone produced by the ante-rior pituitary, which plays a major role in follicular development leading up to ovulation and spermatogenesis. FSH possesses two dissimilar ... -
Follicle-stimulating hormone macroheterogeneity and its effect on receptor conformation
Carney, Abby J. (Wichita State University, 2022-07)Follicle-stimulating hormone (FSH) is a glycoprotein hormone that plays a significant role in gonadal development and fertility. FSH is a heterodimeric glycoprotein composed of a common $\beta$-subunit non-covalently ... -
Human follicle-stimulating hormone glycoform abundance during the normal menstrual cycle in women
Rueda Santos, Monica A. (Wichita State University, 2009-05)Human FSH exists as two major glycoforms, tetra-glycosylated and di-glycosylated hFSH. Tetra-glycosylated FSH possesses both α and β subunit carbohydrates while di-glycosylated hFSH possesses only α subunit carbohydrates. ... -
Urinary follicle-stimulating hormone glycoform analysis by automated western blot
Katta, Sahithi (Wichita State University, 2021-07)Follicle-stimulating hormone (FSH) is one of the glycoprotein hormones synthesized and secreted by the gonadotropic cells of the anterior pituitary gland. In females, FSH stimulates ovarian follicular development and ...