Browsing EECS Faculty Scholarship by Author "Thapa, Niraj"
Now showing items 1-6 of 6
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Comparison of machine learning and deep learning models for network intrusion detection systems
Thapa, Niraj; Liu, Zhipeng; KC, Dukka B.; Gokaraju, Balakrishna; Roy, Kaushik (MDPI AG, 2020-09-30)The development of robust anomaly-based network detection systems, which are preferred over static signal-based network intrusion, is vital for cybersecurity. The development of a flexible and dynamic security system is ... -
A deep learning based approach for prediction of Chlamydomonas reinhardtii phosphorylation sites
Thapa, Niraj; Chaudhari, Meenal; Iannetta, Anthony A.; White, Clarence; Kaushik, Roy; Newman, Robert H.; Hicks, Leslie M.; KC, Dukka B. (Nature, 2021-06-15)Protein phosphorylation, which is one of the most important post-translational modifications (PTMs), is involved in regulating myriad cellular processes. Herein, we present a novel deep learning based approach for ... -
DeepRMethylSite: a deep learning based approach for prediction of arginine methylation sites in proteins
Chaudhari, Meenal; Thapa, Niraj; Roy, Kaushik; Newman, Robert H.; Hiroto, Saigo; KC, Dukka B. (Royal Society of Chemistry, 2020-06-03)Methylation, which is one of the most prominent post-translational modifications on proteins, regulates many important cellular functions. Though several model-based methylation site predictors have been reported, all ... -
DeepSuccinylSite: a deep learning based approach for protein succinylation site prediction
Thapa, Niraj; Chaudhari, Meenal; McManus, Sean; Roy, Kaushik; Newman, Robert H.; Hiroto, Saigo; KC, Dukka B. (Springer, 2020-04-23)Protein succinylation has recently emerged as an important and common post-translation modification (PTM) that occurs on lysine residues. Succinylation is notable both in its size (e.g., at 100 Da, it is one of the larger ... -
DTL-DephosSite: Deep transfer learning based approach to predict dephosphorylation sites
Chaudhari, Meenal; Thapa, Niraj; Ismail, Hamid D.; Chopade, Sandhya; Caragea, Doina; Köhn, Maja; Newman, Robert H.; Kc, Dukka B. (Frontiers Media, 2021-06)Phosphorylation, which is mediated by protein kinases and opposed by protein phosphatases, is an important post-translational modification that regulates many cellular processes, including cellular metabolism, cell migration, ... -
RF-MaloSite and DL-Malosite: Methods based on random forest and deep learning to identify malonylation sites
Al-Barakati, Hussam J.; Thapa, Niraj; Hiroto, Saigo; Roy, Kaushik; Newman, Robert H.; KC, Dukka B. (Elsevier, 2020)Malonylation, which has recently emerged as an important lysine modification, regulates diverse biological activities and has been implicated in several pervasive disorders, including cardiovascular disease and cancer. ...