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dc.contributor.advisorVan Stipdonk, Michael J.en_US
dc.contributor.authorLygrisse, Justinen_US
dc.date.accessioned2010-05-03T18:54:27Z
dc.date.available2010-05-03T18:54:27Z
dc.date.issued2009-05en_US
dc.identifier.othert09024en_US
dc.identifier.urihttp://hdl.handle.net/10057/2424
dc.descriptionThesis (M.S.)--Wichita State University, College of Liberal Arts and Sciences, Dept. of Chemistryen_US
dc.description.abstractThe research presented here details the development of two separate methods for ESI-MS and LC. The first chapter gives an introduction to the first of the methods presented here, the detection of ketamine in alcoholic drinks. The second chapter gives a brief introduction into the relevance of developing a method for investigating clomiphene in biological samples. The third and fourth chapters outline the experimental parameters for the ketamine and clomiphene detection methods, respectively. Included are the parameters used for the mass spectrometer, liquid chromatography, and UV/Visible absorbance spectroscopy as well as the methods for extraction and sample work up. Chapter five outlines the development of a method for detecting and quantifying the date rape drug Ketamine HCl in alcoholic drink matrices. The sixth chapter outlines the development of LC and MS methods for detecting and quantifying clomiphene citrate in fetal calf serum and the initial results for the extraction and detection of clomiphene citrate in meconium. Chapters seven and eight present the conclusions for the ketamine and clomiphene studies, respectively, with directions for future studies.en_US
dc.format.extentxiii, 60 p.en_US
dc.format.extent850941 bytes
dc.format.mimetypeapplication/pdf
dc.language.isoen_USen_US
dc.publisherWichita State Universityen_US
dc.titleDetection and quantification of ketamine and clomiphene in complex matrices by LC and ESI-MSNen_US
dc.typeThesisen_US


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