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dc.contributor.authorSingh, Navdeep
dc.contributor.authorBatra, Uma
dc.contributor.authorKumar, Kamal
dc.contributor.authorAhuja, Neeraj
dc.contributor.authorMahapatro, Anil
dc.date.accessioned2022-05-31T21:08:11Z
dc.date.available2022-05-31T21:08:11Z
dc.date.issued2022-05-15
dc.identifier.citationSingh, N., Batra, U., Kumar, K., Ahuja, N., & Mahapatro, A. (2023). Progress in bioactive surface coatings on biodegradable Mg alloys: A critical review towards clinical translation. Bioactive Materials, 19. https://doi.org/https://doi.org/10.1016/j.bioactmat.2022.05.009
dc.identifier.issn2452-199X
dc.identifier.urihttps://doi.org/10.1016/j.bioactmat.2022.05.009
dc.identifier.urihttps://soar.wichita.edu/handle/10057/23366
dc.descriptionThis is an open access article under the CC BY-NC-ND license.
dc.description.abstractMg and its alloys evince strong candidature for biodegradable bone implants, cardiovascular stents, and wound closing devices. However, their rapid degradation rate causes premature implant failure, constraining clinical applications. Bio-functional surface coatings have emerged as the most competent strategy to fulfill the diverse clinical requirements, besides yielding effective corrosion resistance. This article reviews the progress of biodegradable and advanced surface coatings on Mg alloys investigated in recent years, aiming to build up a comprehensive knowledge framework of coating techniques, processing parameters, performance measures in terms of corrosion resistance, adhesion strength, and biocompatibility. Recently developed conversion and deposition type surface coatings are thoroughly discussed by reporting their essential therapeutic responses like osteogenesis, angiogenesis, cytocompatibility, hemocompatibility, anti-bacterial, and controlled drug release towards in-vitro and in-vivo study models. The challenges associated with metallic, ceramic and polymeric coatings along with merits and demerits of various coatings have been illustrated. The use of multilayered hybrid coating comprising a unique combination of organic and inorganic components has been emphasized with future perspectives to obtain diverse bio-functionalities in a facile single coating system for orthopedic implant applications.
dc.language.isoen_US
dc.publisherElsevier B.V. on behalf of KeAi Communications Co. Ltd.
dc.relation.ispartofseriesBioactive Materials
dc.relation.ispartofseriesVol. 19
dc.subjectMg alloys
dc.subjectCorrosion resistance
dc.subjectBio-functionality
dc.subjectConversion coating
dc.subjectMultilayered hybrid coating
dc.subjectCoating failures
dc.titleProgress in bioactive surface coatings on biodegradable Mg alloys: A critical review towards clinical translation
dc.typePreprint
dc.rights.holder© 2022 The Authors


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