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dc.contributor.authorSimpson, Megan Odettaen_US
dc.contributor.authorHendry, William J. IIIen_US
dc.date.accessioned2009-11-19T21:48:37Z
dc.date.available2009-11-19T21:48:37Z
dc.date.issued2009-05-01en_US
dc.identifier.citationSimpson, Megan and William Hendry (2009). DNA Methylation and its Role in a form of Hormone-Dependent Cancer . In Proceedings: 5th Annual Symposium: Graduate Research and Scholarly Projects. Wichita, KS: Wichita State University, p. 58-59en_US
dc.identifier.urihttp://hdl.handle.net/10057/2313
dc.descriptionPaper presented to the 5th Annual Symposium on Graduate Research and Scholarly Projects (GRASP) held at the Hughes Metropolitan Complex, Wichita State University, May 1, 2009.en_US
dc.descriptionResearch completed at the Department of Biological Sciencesen_US
dc.description.abstractDiethylstilbestrol (DES), a synthetic estrogen, was widely administered to pregnant women between 1947 and 1971 on account of a misconception that it could prevent miscarriages. The offspring of these women were diagnosed with various reproductive tract abnormalities, including cancer. We focused this study on DES-induced abnormalities in the uterus. We screened for altered DNA methylation patterns in uteri from control vs. neonatally DES-treated hamsters using MSRF. Preliminary results show differential DNA methylation patterns in uteri of control vs. DES-treated hamsters. Next we will determine the nucleotide sequence of the differentially methylated genetic elements.en_US
dc.format.extent127684 bytes
dc.format.mimetypeapplication/pdf
dc.language.isoen_USen_US
dc.publisherWichita State University. Graduate Schoolen_US
dc.relation.ispartofseriesGRASPen_US
dc.relation.ispartofseriesv.5en_US
dc.titleDNA methylation and its role in a form of hormone-dependent canceren_US
dc.typeConference paperen_US


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