Browsing URCAF Abstracts 2022 by Author "Beck, Moriah R."
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Defining the interface between palladin and actin using crosslinking mass spectrometry
Liu, David (Wichita State University, 2022-04-15)Palladin was discovered in 2000 and has been shown to play a significant role in actin growth, also known as polymerization, which is a key mechanism in cancer metastasis. A single immunoglobulin domain (Ig3) of palladin ... -
Form and function: Does the source of actin determine functional interactions with palladin?
Urbina, Noely; Klausmeyer, Rachel; Liu, David; Beck, Moriah R. (Wichita State University, 2022-04-15)Actin is one of the most abundant proteins in eukaryotes and regulates individual cell functions such as motility, cell shape, and muscle contractions. Yet, actin cannot work alone and interacts with over 150 actin-binding ... -
Watching actin grow to help understand cancer metastasis
Fater, Aaron (Wichita State University, 2022-04-15)The actin-associated human protein palladin plays a pivotal role in cytoskeletal organization in normal and cancerous cells. In pancreatic and breast cancer cell lines, palladin expression levels have been shown to ...