• Login
    View Item 
    •   Shocker Open Access Repository Home
    • Graduate Student Research
    • GRASP: Graduate Research and Scholarly Projects
    • Proceedings 2009: 5th Annual Symposium: Graduate Research and Scholarly Projects
    • View Item
    •   Shocker Open Access Repository Home
    • Graduate Student Research
    • GRASP: Graduate Research and Scholarly Projects
    • Proceedings 2009: 5th Annual Symposium: Graduate Research and Scholarly Projects
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Nitrofurantoin-Induced pulmonary toxicity.

    View/Open
    GRASP5_85.pdf (111.8Kb)
    Date
    2009-05-01
    Author
    Wilkin, Ryan Todd
    Advisor
    Hale, LaDonna S.; Claiborne, Richard A.
    Metadata
    Show full item record
    Citation
    Wilkin, Ryan Todd, Hale, LaDonna S. and Richard A. Claiborne (2009). Nitrofurantoin-Induced Pulmonary Toxicity. - In Proceedings: 5th Annual Symposium: Graduate Research and Scholarly Projects. Wichita, KS: Wichita State University, p. 182-183
    Abstract
    Background: Nitrofurantoin is commonly prescribed to treat and prevent uncomplicated urinary tract infections. Although generally considered safe, one rare but serious side effect is chronic pulmonary toxicity. Purpose: Describe a single incident of chronic nitrofurantoin-induced pulmonary toxicity that was nearly overlooked, in part, due to poor chart documentation of home medications. Case Report: An 89 year old female presented to the emergency department (ED) with a one month history of fatigue, nonproductive cough, and weakness. Chest radiograph demonstrated extensive interstitial changes with bilateral cyst formation or possible cavitation. Because of incomplete medication histories documented in nursing, ED, and pulmonary consult records, prior chronic nitrofurantoin use was not recognized. On day two of hospitalization, a complete home medication list was obtained and all medications resumed. It was then that the use of nitrofurantoin was recognized and a diagnosis of chronic nitrofurantoin-induced pulmonary toxicity was made. A chest radiograph performed 22 months later demonstrated resolution of toxicity. Conclusion: Poor documentation of home medications coupled with the rarity of occurrence of this adverse reaction and slow insidious onset of symptoms created a diagnostic dilemma for clinicians. Describing this relatively rare adverse reaction to a commonly prescribed antibiotic may remind clinicians to consider drug toxicity in patients who develop new onset of pulmonary symptoms while taking nitrofurantoin. This case also highlights the importance of thorough documentation and awareness of home medications in making accurate diagnoses.
    Description
    Second Place winner of poster presentations at the 5th Annual Symposium on Graduate Research and Scholarly Projects (GRASP) held at the Hughes Metropolitan Complex, Wichita State University, May 1, 2009.

    Research completed at the Department of Physician Assistant, College of Health Professions
    URI
    http://hdl.handle.net/10057/2246
    Collections
    • PA Graduate Student Conference Papers
    • Proceedings 2009: 5th Annual Symposium: Graduate Research and Scholarly Projects

    Browse

    All of Shocker Open Access RepositoryCommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsBy TypeThis CollectionBy Issue DateAuthorsTitlesSubjectsBy Type

    My Account

    LoginRegister

    Statistics

    Most Popular ItemsStatistics by CountryMost Popular Authors

    DSpace software copyright © 2002-2023  DuraSpace
    DSpace Express is a service operated by 
    Atmire NV