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dc.contributor.authorForster, Heather
dc.contributor.authorShuai, Bin
dc.identifier.citationForster, Heather; Shuai, Bin. 2020. RNAi-mediated knockdown of β-1,3-glucan synthase suppresses growth of the phytopathogenic fungus Macrophomina phaseolina. Physiological and Molecular Plant Pathology, vol. 110:art. no. 101486en_US
dc.descriptionClick on the DOI link to access the article (may not be free).en_US
dc.description.abstractCharcoal rot, caused by the fungus Macrophomina phaseolina, affects wide varieties of plant species and may result in serious crop losses. Exogenous siRNAs were applied to target a β-1,3-glucan synthase (MpGLS2) gene in M. phaseolina to test the hypothesis that decreased production of β-1,3-glucan, a major cell wall component, would negatively affect growth of the fungus. Under various testing conditions, fungal growth was suppressed due to siRNA treatments. Importantly, the growth suppression correlated with down regulation of MpGLS2 gene by siRNAs. RNAi-based strategy targeting genes important for cell wall synthesis may provide effective means to control pathogen growth and prevent infection.en_US
dc.description.sponsorshipGrant to HF from the Office of Research and Economic Development at Wichita State University.en_US
dc.relation.ispartofseriesPhysiological and Molecular Plant Pathology;v.110:art. no.101486
dc.subjectMacrophomina phaseolinaen_US
dc.subjectRNA interferenceen_US
dc.subjectSmall interfering RNAen_US
dc.titleRNAi-mediated knockdown of β-1,3-glucan synthase suppresses growth of the phytopathogenic fungus Macrophomina phaseolinaen_US
dc.rights.holder© 2020 Elsevieren_US

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