Browsing Mechanical Engineering by Author "Wamocha, Humphrey Lusenaka"
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CFD analysis of drug carrying magnetic nanocomposite carriers under magnetic fields
Wamocha, Humphrey Lusenaka; Tandel, R.; Lankarani, Hamid M.; Asmatulu, Ramazan (American Society of Mechanical Engineers, 2012)Recently, magnetic targeted drug delivery has been focused on the efficiency of magnetic nanoparticles (MNP) encapsulated in polymeric materials and drug molecules. The MNP can be introduced into the blood stream intravenously ... -
Cytotoxicity of release products from magnetic nanocomposites in targeted drug delivery
Wamocha, Humphrey Lusenaka; Misak, Heath Edward; Song, Zheng; Chu, H.Y.; Chen, Y.Y.; Asmatulu, Ramazan; Yang, Shang-You; Ho, J. C. (Sage Publications, 2011-11-09)The efficacy of chemotherapy can be significantly improved if the therapeutic agent remains localized at the afflicted area and released at controlled rates. Such a targeted drug delivery can be achieved using magnetic ... -
Hydrodynamic behavior of magnetic nanocomposite spheres under magnetic fields
Wamocha, Humphrey Lusenaka; Asmatulu, Ramazan; Ravigururajan, Tiruvadi S. (American Society of Mechanical Engineers, 2012)In the present study, drug carrying magnetic nanocomposite spheres were fabricated using oil-in-oil emulsion/solvent evaporation method and characterized via different techniques. The spheres with a diameter of 200 nm and ... -
Synthesis and biological evaluation of drug-carrying magnetic nanocomposite particles for targeted drug delivery.
Wamocha, Humphrey Lusenaka; Misak, Heath Edward; Asmatulu, Ramazan (Wichita State University. Graduate School, 2009-05-01)Drug-carrying magnetic nanocomposite spheres were synthesized using Co0.5Zn0.5Fe2O4 nanoparticles and poly (D, L-lactide-co-glycolide)(PLGA) for the purpose of magnetic targeted drug delivery. Magnetic nanoparticles (MNP) ... -
Synthesis and characterization of 5-Fu loaded magnetic nanocomposite spheres for advanced drug delivery
Wamocha, Humphrey Lusenaka (Wichita State University, 2010-08)Magnetic targeted drug delivery, the science concerned with the design, characterization and use of magnetic materials as carriers of therapeutic agents presents promising advances in the study of drug delivery and ...