Browsing Mechanical Engineering by Author "Saeednia, Leyla"
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Chitosan and fullerene hybrid hydrogel for drug delivery system with enhanced antitumor cell effects
Saeednia, Leyla; Yao, Li; Asmatulu, Ramazan (Elsevier Ltd, 2022-12-01)Fullerene is a spherical hollow structure composed of carbon atoms. It has emerged in the new development of numerous fullerene-based compounds with a variety of biological targets such as anticancer, cytoprotection, tissue ... -
Electrospun nanocomposite membranes incorporated with PVdF/PVP and carbon blacks for supercapacitor applications
Jabbarnia, Amir; Ghazinezami, Ali; Saeednia, Leyla (Wichita State University. Graduate School, 2014-04-25)Supercapacitors are new generation of energy storage devices using high surface area conductive or semiconductive materials. The supercapacitors show a better performance compared to the other chemical storage devices ... -
Injectable thermosensitive hydrogels as drug delivery systems.
Saeednia, Leyla; Usta, Aybala (Wichita State University. Graduate School, 2013-05-08)Recently, injectable thermosensitive hydrogels have been attracted much attention for the biomedical applications, such as drug delivery and tissue engineering. Injectable hydrogels offer a number of advantages, including ... -
Investigating the mechanical and biological properties of nanoparticles-infused thermosensitive chitosan hydrogels for targeted drug delivery
Saeednia, Leyla (Wichita State University, 2016-05)Targeted drug delivery systems (DDSs) have been widely studied in cancer therapy using various chemotherapy drugs. Due to the toxicity of these cancer drugs, it is desired to target them into the tumor site, hence ... -
Methotrexate loaded magnetic nanoparticles as a targeted drug delivery device
Saeednia, Leyla; Asmatulu, Ramazan (American Society of Mechanical Engineers, 2016)Targeted drug delivery systems have been shown to be promising alternative for the conventional drug delivery methods. Among numerous nanocarriers developed for therapeutic applications, iron oxide magnetic nanoparticles ... -
Preparation and characterization of drug-loaded thermosensitive hydrogels
Saeednia, Leyla; Usta, Aybala; Asmatulu, Ramazan (American Society of Mechanical Engineers, 2014)Hydrogels are the promising classes of polymeric drug delivery systems with the controlled release rates. Among them, injectable thermosensitive hydrogels with transition temperature around the body temperature have been ... -
Sonochemical synthesis of a new nano-scale 1D copper organic coordination polymer; thermal and spectroscopic characterizations
Saeednia, Samira; Iranmanesh, Parvaneh; Rudbari, Hadi Amiri; Saeednia, Leyla (Taylor & Francis Group, 2016-04-02)Single crystal of a new one-dimensional copper organic coordination polymer, 1D-CuOCP, [Cu(HL)NO3](n) 0001">(1) (H2L = [2-[1-(2-hydroxy-propylimino)-ethyl]-phenol]) and its nanostructure, have been synthesized by slow ... -
Structural and biological properties of thermosensitive chitosan-graphene hybrid hydrogels for sustained drug delivery applications
Saeednia, Leyla; Yao, Li; Berndt, Marcus; Cluff, Kim; Asmatulu, Ramazan (John Wiley & Sons, Inc., 2017-09)Chitosan has the ability to make injectable thermosensitive hydrogels which has been highly investigated for drug delivery applications. The addition of nanoparticles is one way to increase the mechanical strength of ... -
Sustained releasing of methotrexate from injectable and thermosensitive chitosan-carbon nanotube hybrid hydrogels effectively controls tumor cell growth
Saeednia, Leyla; Yao, Li; Cluff, Kim; Asmatulu, Ramazan (American Chemical Society, 2019-02-22)Injectable thermosensitive hydrogels have been widely investigated for drug delivery systems. Chitosan (CH) is one of the most abundant natural polymers, and its biocompatibility and biodegradability make it a favorable ...