Show simple item record

dc.contributor.authorRashtchian, Ayoub
dc.contributor.authorNouravarsani, Roya
dc.contributor.authorMiller, Glendon R.
dc.contributor.authorGerlach, E.H.
dc.date.accessioned2019-03-22T19:15:39Z
dc.date.available2019-03-22T19:15:39Z
dc.date.issued1979-07-25
dc.identifier.citationA Rashtchian, R Nouravarsani, G R Miller, E H Gerlach. Increased production of beta-lactamase under anaerobic conditions in some strains of Escherichia coli. Antimicrobial Agents and Chemotherapy Dec 1979, 16 (6) 772-775; DOI: 10.1128/AAC.16.6.772
dc.identifier.issn0066-4804
dc.identifier.urihttp://dx.doi.org/10.1128/AAC.16.6.772
dc.identifier.urihttp://hdl.handle.net/10057/15971
dc.descriptionClick on the DOI link below to access the article (may not be free).
dc.description.abstractA simple biological assay to detect beta-lactamase activity exhibited by selected cultures of Escherichia coli was used to test enzyme production in cells incubated aerobically and anaerobically. Anaerobic incubation resulted in increased size of zones of drug inactivation by some beta-lactamase-producing strains. The beta-lactamase activity of cell lysates was determined iodometrically for aerobically and anaerobically grown cells. The specific beta-lactamase activity for anaerobically grown cells was three to five times greater than for aerobically grown cells. Beta-lactamase production was determined to be constitutive in all strains and to be plasmid mediated, as demonstrated by transfer to E. coli K-12 by conjugation.
dc.language.isoen-US
dc.publisherAmerican Society for Microbiology
dc.relation.ispartofseriesAntimicrobial Agents and Chemotherapy
dc.relation.ispartofseriesv 16, no. 6
dc.subjectBeta-lactamase production
dc.subjectEscherichia coli (E. coli)
dc.subjectAnaerobic condition
dc.titleIncreased production of beta-lactamase under anaerobic conditions in some strains of Escherichia coli
dc.typeArticle
dc.rights.holderCopyright 1979, American Society for Microbiology


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record