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    • LacI-DNA-IPTG Loops: Equilibria among conformations by single-molecule FRET 

      Goodson, Kathy A.; Wang, Zifan; Haeusler, Aaron R.; Kahn, Jason D.; English, Douglas S. (American Chemical Society, 2013-02-13)
      The E. coli Lac repressor (LacI) tetramer binds simultaneously to a promoter-proximal DNA binding site (operator) and an auxiliary operator, resulting in a DNA loop, which increases repression efficiency. Induction of the ...