Browsing Chemistry and Biochemistry by Subject "Neurotoxins"
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2, 2'-and 4, 4'-Cyanines are transporter-independent in vitro dopaminergic toxins with the specificity and mechanism of toxicity similar to MPP+
(Wiley Periodicals, Inc., 2015-11)Specific uptake through dopamine transporter followed by the inhibition of the mitochondrial complex-I have been accepted as the cause of the specific dopaminergic toxicity of 1-methyl-4-phenylpyridinium (MPP+). However, ...