Browsing Chemistry and Biochemistry by Author "Yang, Bing"

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Detecting active deconjugating enzymes with genetically encoded activity-based Ubiquitin and Ubiquitin-like protein probes

Shu, Xin; Liao, Qing-Qing; Li, Shang-Tong; Liu, Lu; Zhang, Xiajun; Zhou, Lianqi; Zhang, Long; Coin, Irene; Wang, Lei; Wu, Haifan; Yang, Bing (American Chemical Society, 2023-01-17)

Post-translational modification of proteins by Ubiquitin (Ub) and Ubiquitin-like proteins (Ubls) can be reversed by deconjugating enzymes, which have been implicated in different pathways and associated with various human ...
Uncover new reactivity of genetically encoded alkyl bromide non-canonical amino acids

Shu, Xin; Asghar, Sana; Yang, Fan; Li, Shang-Tong; Wu, Haifan; Yang, Bing (Frontiers Media S.A., 2022-02-18)

Genetically encoded non-canonical amino acids (ncAAs) with electrophilic moieties are excellent tools to investigate protein-protein interactions (PPIs) both in vitro and in vivo. These ncAAs, including a series of alkyl ...