Browsing Chemistry and Biochemistry by Author "Sands, Howard"

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Inhibition of human leukocyte proteinase 3 by a novel recombinant serine proteinase inhibitor (LEX032)

Groutas, William C.; Ruan, Sumei; Kuang, Rongze; Hook, Jerry B.; Sands, Howard (Elsevier, 1997-04-28)

The interaction of a bioengineered serpin (LEX032) with human leukocyte proteinase 3 (PR 3) has been investigated. LEX032 was found to be a time-dependent inhibitor of PR 3, forming a highly-stable enzyme-inhibitor complex ...