Browsing Chemistry and Biochemistry by Author "Gong, Maojun"
Now showing items 1-14 of 14
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Alternate injections coupled with flow-gated capillary electrophoresis for rapid and accurate quantitative analysis of urine samples
Zhu, Qingfu; Zhang, Qiyang; Zhang, Ning; Gong, Maojun (Elsevier B.V., 2017-07-25)Capillary electrophoresis (CE) is a powerful separation technique with advantages over HPLC in terms of separation efficiency, speed, and cost. However, CE suffers in poor reproducibility in quantitative chemical analysis, ... -
CE-LIF coupled with PDMS-interconnected microfluidic systems for rapid separations of neurotransmitters
Zhang, Qiyang; Maddukuri, Naveen (Wichita State University. Graduate School, 2014-04-25)In vivo measurement of neurotransmitters in cerebrospinal fluidic (CSF) is an effective method to monitor neuronal activities. Microdialysis coupled with HPLC or capillary electrophoresis (CE) is a powerful approach for ... -
A direct and rapid method to determine cyanide in urine by capillary electrophoresis
Zhang, Qiyang; Maddukuri, Naveen; Gong, Maojun (Elsevier B.V., 2015-10-02)Cyanides are poisonous chemicals that widely exist in nature and industrial processes as well as accidental fires. Rapid and accurate determination of cyanide exposure would facilitate forensic investigation, medical ... -
Double-branch capillary electrophoresis by using microfluidic switch for alternate injections
Zhang, Qiyang (Wichita State University, 2016-04-29)Capillary electrophoresis (CE) is an analytical tool which has gained great interests during the past decade. The main attractions of CE are its fast, high-throughput and highly efficient separations. However, conventional ... -
Enhancing detection sensitivity for measuring amino neurotransmitters with flow-gated capillary electrophoresis
Maddukuri, Naveen (Wichita State University, 2020-07)Capillary electrophoresis (CE) commences as a promising technique for analyzing a variety of biological substances and has been used in bioanalytical and biopharmaceutical applications. Flow-gated CE has numerous advantages ... -
Flow-gated capillary electrophoresis for rapid analysis of biological samples
Zhang, Qiyang (Wichita State University, 2016-07)Capillary electrophoresis (CE) and related technologies have been utilized with great success for a variety of bioanalytical applications. CE has the advantages of decreased analysis time, integrated sample processing, ... -
Flow-gated capillary electrophoresis: a powerful technique for rapid and efficient chemical separation
Gong, Maojun; Zhang, Ning; Maddukuri, Naveen (Royal Society of Chemistry, 2018-05-30)Flow-gated capillary electrophoresis (CE) is a hybrid of conventional and microchip CE since it employs a fused silica capillary as the separation channel while taking advantage of the rapid flow-gated injection that is ... -
On-line preconcentration of fluorescent derivatives of catecholamines in cerebrospinal fluid using flow-gated capillary electrophoresis
Zhang, Qiyang; Gong, Maojun (Elsevier B.V., 2016-06-10)Flow-gated capillary electrophoresis (CE) coupled with microdialysis has become an important tool for in vivo bioanalytical measurements because it is capable of performing rapid and efficient separations of complex ... -
Online preconcentration of high-salt samples using pressure-assisted field-amplified sample injection in flow-gated capillary electrophoresis
Maddukuri, Naveen; Gong, Maojun (Wichita State University, 2019-04-26)Capillary electrophoresis (CE) is a valuable separation method; however, its detection sensitivity is often limited by the small sample volumes injected. Different strategies have been developed to enhance the sensitivity, ... -
Prototyping of poly(dimethylsiloxane) interfaces for flow gating, reagent mixing, and tubing connection in capillary electrophoresis
Zhang, Qiyang; Gong, Maojun (Elsevier B.V., 2014-01-10)Integrated microfluidic systems coupled with electrophoretic separations have broad application in biologic and chemical analysis. Interfaces for the connection of various functional parts play a major role in the performance ... -
Rapid amino acid analysis of beers using flow-gated capillary electrophoresis coupled with side-by-side calibration
Zhu, Qingfu; Zhang, Ning; Gong, Maojun (Royal Society of Chemistry, 2017-08-21)Amino acid analysis is an important procedure to measure free amino acids (AAs) in various samples including proteins, blood plasma, urine, foods and beverages. Due to the complexity of these samples, chemical separations ... -
Rapid determination of free prolyl dipeptides and 4-hydroxyproline in urine using flow-gated capillary electrophoresis
Zhang, Ning; Zhu, Qingfu; Gong, Maojun (Springer, 2017-12)Unhydrolyzed prolyl hydroxyproline (Pro-Hyp) and total 4-hydroxyproline (Hyp) in urine have been suggested as disease biomarkers for bone turnover and osteoporosis. Here, a rapid method was developed to accurately and ... -
Rapid determination of free prolyl dipeptides and 4-hydroxyproline in urine using flow-gated capillary electrophoresis
Zhang, Ning (Wichita State University, 2018-04-27)4-hydroxyproline (Hyp) and prolyl dipeptides such as prolyl hydroxyproline (Pro-Hyp) have been found as disease biomarkers in the diagnosis of bone turnover and osteoporosis. To determine these compounds in human urine ... -
Rapid labeling of amino acid neurotransmitters with a fluorescent thiol in the presence of o-phthalaldehyde
Maddukuri, Naveen; Zhang, Qiyang; Zhang, Ning; Gong, Maojun (John Wiley & Sons, Inc., 2017-02)LIF detection often requires labeling of analytes with fluorophores; and fast fluorescent derivatization is valuable for high-throughput analysis with flow-gated CE. Here, we report a fast fluorescein-labeling scheme for ...