Browsing Chemistry and Biochemistry by Title
Now showing items 456-475 of 671
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Photosynthetic reaction center mimicry of a "special pair" dimer linked to electron acceptors by a supramolecular approach: self-assembled cofacial zinc porphyrin dimer complexed with fullerene(s)
(John Wiley and Sons, 2007-01-01)Biomimetic bacterial photosynthetic reaction center complexes have been constructed using well-defined self-assembled supramolecular approaches. The "special pair" donor, a cofacial porphyrin dimer, was formed via potassium ... -
Photosynthetic reaction center mimicry: low reorganization energy driven charge stabilization in self-assembled cofacial zinc phthalocyanine dimer-fullerene conjugate
(American Chemical Society, 2009-07-01)By employing well-defined self-assembly methods, a biomimetic bacterial photosynthetic reaction center complex has been constructed, and photoinduced electron transfer originating in this supramolecular donor-acceptor ... -
Physical, photophysical and structural properties of ruthenium(II) complexes containing a tetradentate bipyridine ligand
(Royal Society of Chemistry, 2008-06-28)The focus of this report is the synthesis and properties of two new analogues of ruthenium(ii) tris-bipyridine, a monomer and dimer. The complexes contain the ligand 6,6'-(ethan-1,2-diyl)bis-2,2'-bipyridine (O-bpy) which ... -
Physico-chemical studies of interactions of water soluble brominated porphyrins with DNA
(Wichita State University. Graduate School., 2006-04-28) -
Plausible molecular mechanism for activation by fumarate and electron transfer of the dopamine beta-mono-oxygenase reaction
(American Chemical Society, 2002-10-01)A series of fumarate analogues has been used to explore the molecular mechanism of the activation of dopamine beta-mono-oxygenase by fumarate. Mesaconic acid (MA) and trans -glutaconic acid (TGA) both activate the enzyme ... -
Polymer nano-composite materials based on hyperbranched polymers in petroleum applications
(Wichita State University, 2021-04-02)The Petroleum sector is facing a wide variety of challenges in finding economically and safe solutions for the corrosion problem, in which a tremendous amount of different metals, especially carbon steel, are consumed as ... -
Polymeric biomaterials for wound healing applications: a comprehensive review
(Taylor and Francis Ltd., 2022-06-19)Chronic wounds have been a global health threat over the past few decades, requiring urgent medical and research attention. The factors delaying the wound-healing process include obesity, stress, microbial infection, aging, ... -
Polypyridyl complexes of uracil derivatives attached to 2,2 '-pyridyl
(American Chemical Society, 2018)Three ligands obtained by the condensation of 2,2'-pyridyl with 5,6-diaminouracil, 5,6-diamino-1-methyluracil and 5,6-diamino-1,3-dimethyluracil were synthesized and crystal structures of the uracil and di-Me ... -
Porphyrin molecules that selectively bind to the phosphatidylglycerol (PG) head group, a lipid found in bacterial membrane
(Wichita State University, 2019-04-26)Porphyrin molecules that selectively bind to the phosphatidylglycerol (PG) head group, a lipid found in bacterial membrane have been previously reported by our research group. A tetrakis-ammonium glycine picket porphyrin ... -
Potassium ion controlled switching of intra- to intermolecular electron transfer in crown ether appended free-base porphyrin-fullerene donor-acceptor systems
(American Chemical Society, 2006-04-06)Photoinduced electron transfer in intramolecularly interacting free-base porphyrin bearing one or four 18-crown-6 ether units at different positions of the porphyrin macrocycle periphery and pristine fullerene was investigated ... -
Potent and specific inhibition of human leukocyte elastase, cathepsin G and proteinase 3 by sulfone derivatives employing the 1,2,5-thiadiazolidin-3-one 1,1 dioxide scaffold
(Elsevier, 1998-06-01)This paper describes the results of structure-activity relationship studies in a series of heterocyclic mechanism-based inhibitors based on the 1,2,5-thiadiazolidin-3-one 1,1 dioxide scaffold I and capable of interacting ... -
Potent inhibition of enterovirus D68 and human rhinoviruses by dipeptidyl aldehydes and alpha-ketoamides
(Elsevier Ltd., 2016-01)Enterovirus D68 (EV-D68) is an emerging pathogen responsible for mild to severe respiratory infections that occur mostly in infants, children and teenagers. EV-D68, one of more than 100 non-polio enteroviruses, is acid-labile ... -
Potent inhibition of feline coronaviruses with peptidyl compounds targeting coronavirus 3C-like protease
(Elsevier, 2012-11-28)Feline coronavirus infection is common among domestic and exotic felid species and usually associated with mild or asymptomatic enteritis; however, feline infectious peritonitis (FIP) is a fatal disease of cats that is ... -
Potent inhibition of human leukocyte elastase by 1,2,5-thiadiazolidin-3-one 1,1 dioxide-based sulfonamide derivatives
(Elsevier, 2004-09-15)The design, synthesis, and in vitro biochemical evaluation of a class of mechanism-based inhibitors of human leukocyte elastase (HLE) that incorporate in their structure a 1,2,5-thiadiazolidin-3-one 1,1 dioxide scaffold ... -
Potent inhibition of norovirus 3CL protease by peptidyl α-ketoamides and α-ketoheterocycles
(Elsevier, 2012-05-26)A series of structurally-diverse α-ketoamides and α-ketoheterocycles was synthesized and subsequently investigated for inhibitory activity against norovirus 3CL protease in vitro, as well as anti-norovirus activity in a ... -
Potent inhibition of norovirus by dipeptidyl α-hydroxyphosphonate transition state mimics
(Elsevier, 2013-11)The design, synthesis, and evaluation of a series of dipeptidyl α-hydroxyphosphonates is reported. The synthesized compounds displayed high anti-norovirus activity in a cell-based replicon system, as well as high enzyme ... -
Potent inhibition of Norwalk virus by cyclic sulfamide derivatives
(Elsevier, 2011-10-15)A new class of compounds that exhibit anti-norovirus activity in a cell-based system and embody in their structure a cyclosulfamide scaffold has been identified. The structure of the initial hit (compound 2a, ED(50) 4 µM, ... -
Potent inhibition of serine proteases by heterocyclic sulfide derivatives of 1,2,5-thiadiazolidin-3-one 1,1 dioxide
(Elsevier, 2000-07-01)The existence of subtle differences in the Sn' subsites of closely-related (chymo)trypsin-like serine proteases, and the fact that the 1,2,5-thiadiazolidin-3-one 1,1 dioxide scaffold docks to the active site of (chymo)trypsin-like ... -
Potent norovirus inhibitors based on the acyclic sulfamide scaffold
(Elsevier, 2012-03-15)The development of small molecule therapeutics to combat norovirus infection is of considerable interest from a public health perspective because of the highly contagious nature of noroviruses. A series of amino acid-derived ... -
Potent protease inhibitors of highly pathogenic lagoviruses: Rabbit hemorrhagic disease virus and European brown hare syndrome virus
(American Society for Microbiology, 2022-06-29)Rabbit hemorrhagic disease (RHD) and European brown hare syndrome (EBHS) are highly contagious diseases caused by lagoviruses in the Caliciviridae family. These infectious diseases are associated with high mortality and a ...