Browsing Chemistry and Biochemistry by Title
Now showing items 33-52 of 630
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Anion-complexation-induced stabilization of charge separation
(American Chemical Society, 2009-11-11)A supramolecular oligochromophoric system possessing exclusive binding sites for both a guest electron acceptor and an anionic cofactor species is developed, and anion-binding-induced stabilization of the charge-separated ... -
Anthrax toxin protective antigenuInsights into molecular switching from prepore to pore
(Cambridge University Press, 2012-01)The protective antigen is a key component of the anthrax toxin, as it allows entry of the enzymatic components edema factor and lethal factor into the host cell, through the formation of a membrane spanning pore. This event ... -
Anti-norovirus therapeutics: a patent review (2010-2015)
(Taylor & Francis Group, 2016-03-03)Introduction: Human noroviruses are the primary causative agents of acute gastroenteritis and are a pressing public health burden worldwide. There are currently no vaccines or small molecule therapeutics available for the ... -
Antifungal activity of a series of 1,2-benzisothiazol-3(2H)-one derivatives
(Elsevier, 2011-10-01)A series of broad-spectrum antifungal agents based on the 1,2-benzisothiazol-3(2H)-one scaffold is reported. Preliminary structure-activity relationship studies have established the importance of the presence of the ... -
Antifungal drug discovery: the process and outcomes
(Future Medicine Ltd, 2014-06)New data suggest that the global incidence of several types of fungal diseases have traditionally been under- documented. Of these, mortality caused by invasive fungal infections remains disturbingly high, equal to or ... -
Antiviral drug discovery: norovirus proteases and development of inhibitors
(MDPI AG, Basel, Switzerland, 2019-02-25)Proteases are a major enzyme group playing important roles in a wide variety of biological processes in life forms ranging from viruses to mammalians. The aberrant activity of proteases can lead to various diseases; ... -
Apparent inhibition by arginine of macrocyclic b ion formation from singly charged protonated peptides
(Springer, 2010-08-01)There is now strong evidence for the existence of macrocyclic isomers of b(n)(+) ions, the formation and subsequent opening of which can lead to loss of sequence information from protonated peptides in multiple-stage tandem ... -
Application of photoexcited states of Re (I) metal complexes to solar energy conversion
(American Chemical Society, 2014-03-16)Dye sensitized solar cells (Grätzel Cell) have attracted significant attention as promising next generation photovoltaic devices. In a photovoltaic cell, the dye sensitizers anchored to mesoporous thin films made of the ... -
Application of spherical and other polymers in capillary zone electrophoresis: separation of antiviral drugs and deoxyribonucleoside phosphates by different principles
(Elsevier, 1996-12-20)Soluble polymers of linear chains with limited branching and spherical polymers (limit dextrins and sucrose, such as Dextran and Ficoll (Pharmacia Chemicals), yielding lower viscosities, are examined here for the separation ... -
Applications of diffuse reflectance near-infrared spectroscopy and cure kinetics study by differential scanning calorimetry to selected thermosetting polymer-based systems of interest in the aviation industry
(Wichita State University, 2012-05)Diffuse Reflectance Near-Infrared (near-IR) Spectroscopy combined with Partial Least Squares (PLS) regression was used to determine the moisture content and degree of cure in unfilled epoxy resins, carbon-reinforced epoxy ... -
Applying band gap engineering to tune the linear optical and nonlinear optical properties of noncentrosymmetric chalcogenides $La_4Ge_3Se_X S_{12- x} (x = 0, 2, 4, 6, 8, 10)$
(Royal Society of Chemistry, 2021-09-10)$La_4Ge_3S_{12}$ was structurally characterized in 1974 without any optical or nonlinear optical properties reported. Herein we report that the acentric crystal structure of $La_4Ge_3S_{12}$ has been confirmed by single-crystal ... -
Are SH-SY5Y and MN9D cell lines truly dopaminergic?
(Wichita State University. Graduate School., 2007-04-27)SH-SY5Y and MN9D cell lines are commonly used dopaminergic models in studies related to neurotoxicity, oxidative stress, and neurodegenerative diseases. Early studies suggested that SH-SY5Y cells do not convert intracellular ... -
Ascorbate based novel high affinity alternate reductants and competitive inhibitors of dopamine beta-monooxygenase
(Elsevier, 1994-04-15)A series of ascorbate derivatives has been used to examine the specificity and the chemistry of the reduction site of dopamine beta-monooxygenase (D beta M). Replacement of the 6-OH group of ascorbic acid with either bromine ... -
Assessing the Dipole Moments and Directional Cross Sections of Proteins and Complexes by Differential Ion Mobility Spectrometry
(American Chemical Society, 2022-05-02)Ion mobility spectrometry (IMS) has become a mainstream approach to fractionate complex mixtures, separate isomers, and assign the molecular geometries. All modalities were grouped into linear IMS (based on the absolute ... -
Ba6(CuxZy)Sn4S16(Z = Mg, Mn, Zn, Cd, In, Bi, Sn): High chemical flexibility resulting in good nonlinear-optical properties
(American Chemical Society, 2022-02-07)Seven acentric sulfides Ba6(CuxZy)Sn4S16 (Z = Mg, Mn, Zn, Cd, In, Bi, Sn) were grown by a high-temperature salt flux method. The crystal structures of the Ba6(CuxZy)Sn4S16 (Z = Mg, Mn, Zn, Cd, In, Bi, Sn) compounds were ... -
Binding of the von Willebrand factor A domain of capillary morphogenesis protein 2 to anthrax protective antigen vaccine reduces immunogenicity in mice
(NLM (Medline), 2020-01)Protective antigen (PA) is a component of anthrax toxin that can elicit toxin-neutralizing antibody responses. PA is also the major antigen in the current vaccine to prevent anthrax, but stability problems with recombinant ... -
Binding sites of a positron emission tomography imaging agent in Alzheimer’s β amyloid fibrils studied using 19f solid-state NMR
(ACS Publications, 2022-01-11)Amyloid imaging by positron emission tomography (PET) is an important method for diagnosing neurodegenerative disorders such as Alzheimer’s disease. Many 11C- and 18F-labeled PET tracers show varying binding capacities, ... -
Binding, electrochemical activation, and cleavage of DNA by cobalt(II) tetrakis-N-methylpyridyl porphyrin and its beta-pyrrole brominated derivative
(American Chemical Society, 2006-11-01)The binding of nucleic acids by water-soluble cobalt(II) tetrakis-N-methylpyridyl porphyrin, (TMPyP)Co, and its highly electron-deficient derivative cobalt(II) tetrakis-N-methyl pyridyl-beta-octabromoporphyrin, (Br(8)TMPyP)Co, ... -
Biomimetic solar cells
(Wichita State University. Graduate School, 2010-04-23)Eco friendly energy resources are becoming important due to the predicted oil depletion and soared CO₂ emission. Of available alternatives, solar energy finds special attention due to its vast availability and high power ... -
Bionano donor-acceptor hybrids of porphyrin, ssDNA, and semiconductive single-wall carbon nanotubes for electron transfer via porphyrin excitation
(American Chemical Society, 2011-12)Photoinduced electron transfer in self-assemblies of porphyrins ion-paired with ssDNA wrapped around single-wall carbon nanotubes (SWCNTs) has been reported. To accomplish the three-component hybrids, two kinds of ...