Browsing Chemistry and Biochemistry by Title
Now showing items 25-44 of 648
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Advances in the use of cyclodextrins as chiral selectors in capillary electrokinetic chromatography: fundamentals and applications
(Springer Berlin Heidelberg, 2016-11)Capillary electrokinetic chromatography is generally recognized as a versatile and robust capillary electromigration technique for the separation of enantiomers. In this mode, one or more chiral selectors are added to the ... -
Affinity chromatography of glucose dehydrogenase
(Springer, 1988-01-15)Porcine liver beta-D-glucose dehydrogenase, a multi-functional protein, has been purified to apparent homogeneity. The enzyme has been separated from the endoplasmic reticulum using Triton X-114 and further purified using ... -
Aggregation models of potential cyclical trimethylsulfonium dicyanamide ionic liquid clusters
(American Chemical Society, 2009-02-19)Raman and infrared spectra of trimethylsulfonium dicyanamide [(CH(3))(3)SN(CN)(2)] are reported and accurately reproduced by DFT methods (B3LYP and B3PW91), MP2, and MP3, and to a lesser extent by the RHF method. The ... -
Altered acetylcholinesterase activity (AChE) and maze performance of developing rats (Rattus norvegicus) following mesencephalic electrical brain stimulation
(Springer-Verlag, 1977-11-17)Cortical arousal was altered by electrical brain stimulation (EBS) to the mesencephalic ascending reticular formation beginning at 27 days of age and administered 2 h/day for either 14 or 28 days. Subjects receiving brain ... -
Alternate injections coupled with flow-gated capillary electrophoresis for rapid and accurate quantitative analysis of urine samples
(Elsevier B.V., 2017-07-25)Capillary electrophoresis (CE) is a powerful separation technique with advantages over HPLC in terms of separation efficiency, speed, and cost. However, CE suffers in poor reproducibility in quantitative chemical analysis, ... -
Amino acid-derived 1,2-benzisothiazolinone derivatives as novel small-molecule antifungal inhibitors: identification of potential genetic targets
(American Society of Microbiology, 2012-09)We have identified four synthetic compounds (DFD-VI-15, BD-I-186, DFD-V-49, and DFD-V-66) from an amino acid-derived 1,2-benzisothiazolinone (BZT) scaffold that have reasonable MIC50 values against a panel of fungal ... -
Amino acid-derived phthalimide and saccharin derivatives as inhibitors of human leukocyte elastase, cathepsin G, and proteinase 3
(Elsevier, 1996-08-15)Amino acid-derived phthalimide and saccharin derivatives have been investigated for their inhibitory activity toward the serine proteinases human leukocyte elastase, cathepsin G, and proteinase 3. The saccharin derivatives ... -
An investigation of various methods for the volumetric determination of antimony
(Wichita State University, 1932-05)This invesigation was prompted by the fact that a local industrial plant was unable to make satisfactory determinations of the antimony content of the low melting point alloys used in their products. The problem presented ... -
Analysis of 1-methyl-4-phenylpyridinium derivatives in caenorhabtis elegans
(Wichita State University, 2018-04-27)Parkinson's disease (PD) is a neurodegenerative disease that affects more than 10 million people worldwide and costs 25 billion dollars in the United States alone. Despite its notoriety, the etiology of PD not fully ... -
Analysis of enzyme and solvent dynamics of Candida antarctica lipase B in non-aqueous solvents using molecular dynamics simulations
(American Chemical Society, 2014-08-10)Solvents play a major role in changing biomolecule structure, dynamics and functions. The main objective of this project is to use molecular dynamics simulations to shed light on enzyme-solvent interactions between Candida ... -
Anion-complexation-induced stabilization of charge separation
(American Chemical Society, 2009-11-11)A supramolecular oligochromophoric system possessing exclusive binding sites for both a guest electron acceptor and an anionic cofactor species is developed, and anion-binding-induced stabilization of the charge-separated ... -
Anthrax toxin protective antigenuInsights into molecular switching from prepore to pore
(Cambridge University Press, 2012-01)The protective antigen is a key component of the anthrax toxin, as it allows entry of the enzymatic components edema factor and lethal factor into the host cell, through the formation of a membrane spanning pore. This event ... -
Anti-norovirus therapeutics: a patent review (2010-2015)
(Taylor & Francis Group, 2016-03-03)Introduction: Human noroviruses are the primary causative agents of acute gastroenteritis and are a pressing public health burden worldwide. There are currently no vaccines or small molecule therapeutics available for the ... -
Antifungal activity of a series of 1,2-benzisothiazol-3(2H)-one derivatives
(Elsevier, 2011-10-01)A series of broad-spectrum antifungal agents based on the 1,2-benzisothiazol-3(2H)-one scaffold is reported. Preliminary structure-activity relationship studies have established the importance of the presence of the ... -
Antifungal drug discovery: the process and outcomes
(Future Medicine Ltd, 2014-06)New data suggest that the global incidence of several types of fungal diseases have traditionally been under- documented. Of these, mortality caused by invasive fungal infections remains disturbingly high, equal to or ... -
Antiviral drug discovery: norovirus proteases and development of inhibitors
(MDPI AG, Basel, Switzerland, 2019-02-25)Proteases are a major enzyme group playing important roles in a wide variety of biological processes in life forms ranging from viruses to mammalians. The aberrant activity of proteases can lead to various diseases; ... -
Apparent inhibition by arginine of macrocyclic b ion formation from singly charged protonated peptides
(Springer, 2010-08-01)There is now strong evidence for the existence of macrocyclic isomers of b(n)(+) ions, the formation and subsequent opening of which can lead to loss of sequence information from protonated peptides in multiple-stage tandem ... -
Application of photoexcited states of Re (I) metal complexes to solar energy conversion
(American Chemical Society, 2014-03-16)Dye sensitized solar cells (Grätzel Cell) have attracted significant attention as promising next generation photovoltaic devices. In a photovoltaic cell, the dye sensitizers anchored to mesoporous thin films made of the ... -
Application of spherical and other polymers in capillary zone electrophoresis: separation of antiviral drugs and deoxyribonucleoside phosphates by different principles
(Elsevier, 1996-12-20)Soluble polymers of linear chains with limited branching and spherical polymers (limit dextrins and sucrose, such as Dextran and Ficoll (Pharmacia Chemicals), yielding lower viscosities, are examined here for the separation ... -
Applications of diffuse reflectance near-infrared spectroscopy and cure kinetics study by differential scanning calorimetry to selected thermosetting polymer-based systems of interest in the aviation industry
(Wichita State University, 2012-05)Diffuse Reflectance Near-Infrared (near-IR) Spectroscopy combined with Partial Least Squares (PLS) regression was used to determine the moisture content and degree of cure in unfilled epoxy resins, carbon-reinforced epoxy ...