Browsing Chemistry and Biochemistry by Title
Now showing items 685-691 of 691
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Valence tautomerism induced nucleophilic ipso substitution in a coordinated tetrabromocatecholate ligand and diverse catalytic activity mimicking the function of phenoxazinone synthase
(Elsevier B.V., 2016-02)Two new manganese(III) complexes, [pyH][Mn(Br(4)Cat)(2)(PY)1 (1) and [Mn(Br(4)Cat)(Br(3)PYCat)(PY)(2)] (2), where py is pyridine, Br(4)CatH(2) is tetrabromocatechol and Br(3)pyCatH(2) is 3,5,6-tribromo-4-pyridiniumcatechol, ... -
Vesicular monoamine transporter substrate/inhibitor activity of MPTP/MPP+ derivatives: a structure-activity study
(American Chemical Society, 2008-02-28)The active metabolite of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), N-methyl-4-phenylpyridinium (MPP(+)), selectively destroys the dopaminergic neurons and induces the symptoms of Parkinson's disease. Inhibition ... -
Vesicular monoamine transporters: structure-function, pharmacology, and medicinal chemistry
(John Wiley and Sons, 2011-07-01)Vesicular monoamine transporters (VMAT) are responsible for the uptake of cytosolic monoamines into synaptic vesicles in monoaminergic neurons. Two closely related VMATs with distinct pharmacological properties and tissue ... -
Viral and fungal inhibitors
(United States Patent and Trademark Office, 2013-08-20)Novel classes of viral and fungal inhibitors are disclosed. These compounds are useful in treating, preventing, and/or ameliorating viral infections such as, for example, Hepatitis C Virus, West Nile Virus, Dengue Virus, ... -
Water Soluble Porphyrin based Solar Cell
(Wichita State University. Graduate School, 2011-05-04)Porphyrins are organic chromophores with structure very close to naturally occurring pigment in leaves Chlorophyll. In addition, blood cells are red due to iron porphyrins. These versatile porphyrins are simple to synthesize ... -
What does that molecule look like? Using tandem mass spectrometry, computational chemistry and vibrational spectroscopy to determine molecular structure
(Wichita State University. Graduate School, 2009-05-01)Scientists wanting to determine the structure of a molecule have many tools at their disposal. Tandem mass spectrometry (MS/MS) allows one to study the fragmentation pathways of molecules, examining how a molecule will ... -
X-ray snapshot of the mechanism of inactivation of human neutrophil elastase by 1,2,5-thiadiazolidin-3-one 1,1-dioxide derivatives
(American Chemical Society, 2008-04-10)The mechanism of action of a general class of mechanism-based inhibitors of serine proteases, including human neutrophil elastase (HNE), has been elucidated by determining the X-ray crystal structure of an enzyme-inhibitor ...