Browsing Chemistry and Biochemistry by Title
Now showing items 663-682 of 682
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Ultrafast photoinduced energy and electron transfer in multi-modular donor-acceptor conjugates
(Wiley-Blackwell, 2012-10)New multi-modular donoracceptor conjugates featuring zinc porphyrin (ZnP), catechol-chelated boron dipyrrin (BDP), triphenylamine (TPA) and fullerene (C60), or naphthalenediimide (NDI) have been newly designed and synthesized ... -
Ultrafast singlet-singlet energy transfer in self-assembled via metal-ligand axial coordination of free-base porphyrin-zinc phthalocyanine and free-base porphyrin-zinc naphthalocyanine dyads
(American Chemical Society, 2010-01-14)Singlet-singlet energy transfer in self-assembled via axial coordination of imidazole-appended (at different positions of one of the meso-phenyl entities) free-base tetraphenylporphyrin, H(2)PIm, to either zinc phthalocyanine, ... -
Ultrahigh-resolution differential ion mobility separations of conformers for proteins above 10 kDa: onset of dipole alignment?
(American Chemical Society, 2014-11-04)Biomacromolecules tend to assume numerous structures in solution or the gas phase. It has been possible to resolve disparate conformational families but not unique geometries within each, and drastic peak broadening has ... -
Ultraviolet-curable cycloaliphatic polyesters containing spiroacetal moieties for application as powder coatings
(American Chemical Society, 2022-03-15)Thermosetting cycloaliphatic powder coatings that exhibit good weatherability, corrosion resistance, and mechanical properties have been desired for some time. Unfortunately, most cycloaliphatic resins have glass transition ... -
Uncover new reactivity of genetically encoded alkyl bromide non-canonical amino acids
(Frontiers Media S.A., 2022-02-18)Genetically encoded non-canonical amino acids (ncAAs) with electrophilic moieties are excellent tools to investigate protein-protein interactions (PPIs) both in vitro and in vivo. These ncAAs, including a series of alkyl ... -
Understanding fluorine chemical shifts and the molecular properties of organic molecules
(Wichita State University, 2018-05)Fluorinated molecules have emerged as important probes in drug design, and as strategies for enhancing protein stability and altering physicochemical properties of biological systems. Fluorine NMR plays a crucial role ... -
Urethane methacrylate reactive diluents for UV-curable polyester powder coatings
(Springer, 2021-01-15)Three urethane methacrylates, one monofunctional derivative and two di-functional derivatives with different chain lengths were used as reactive diluents in UV-curable polyester powder coatings. Each reactive diluent was ... -
Use of a high frequency oscillator to detect changes occuring in solids upon heating
(Wichita State University, 1951-05) -
Use of the 1,2,5-thiadiazolidin-3-one 1,1 dioxide and isothiazolidin-3-one 1,1 dioxide scaffolds in the design of potent inhibitors of serine proteinases
(Elsevier, 1998-03-03)The attachment of a phosphate leaving group to the 1,2,5-thiadiazolidin-3-one 1,1 dioxide and isothiazolidin-3-one 1,1 dioxide scaffolds was found to yield highly potent, time-dependent inhibitors of human leukocyte elastase ... -
Using ion mobility spectrometry to resolve isotopomers, identify isomers by isotopologic shifts, and predict mobility changes for post-translationally modified peptides
(Wichita State University, 2017-05)Differential or field asymmetric waveform ion mobility spectrometry (FAIMS) operating at high electric fields fully resolves isotopic isomers for a peptide with labeled residues. The naturally present isotopes, alone and ... -
Using surfactant-based colloidal systems to promote photoinduced synthesis of silver nanoparticles
(Wichita State University, 2018-07)This thesis focuses on the photo-initiated synthesis of silver nanoparticles in water with low concentration of stabilizing agents to investigate the role that surfactants, specifically their charge, plays in the synthesis. ... -
Utilization of the 1,2,3,5-thiatriazolidin-3-one 1,1-dioxide scaffold in the design of potential inhibitors of human neutrophil proteinase 3
(Elsevier, 2010-02-01)The S' subsites of human neutrophil proteinase 3 (Pr 3) were probed by constructing diverse libraries of compounds based on the 1,2,3,5-thiatriazolidin-3-one 1,1-dioxide using combinational and click chemistry methods. The ... -
Utilization of the 1,2,5-thiadiazolidin-3-one 1,1 dioxide scaffold in the design of potent inhibitors of serine proteases: SAR studies using carboxylates
(Elsevier, 2000-05-01)A series of carboxylate derivatives based on the 1,2,5-thiadiazolidin-3-one 1,1 dioxide and isothiazolidin-3-one 1,1 dioxide scaffolds has been synthesized and the inhibitory profile of these compounds toward human leukocyte ... -
Valence tautomerism induced nucleophilic ipso substitution in a coordinated tetrabromocatecholate ligand and diverse catalytic activity mimicking the function of phenoxazinone synthase
(Elsevier B.V., 2016-02)Two new manganese(III) complexes, [pyH][Mn(Br(4)Cat)(2)(PY)1 (1) and [Mn(Br(4)Cat)(Br(3)PYCat)(PY)(2)] (2), where py is pyridine, Br(4)CatH(2) is tetrabromocatechol and Br(3)pyCatH(2) is 3,5,6-tribromo-4-pyridiniumcatechol, ... -
Vesicular monoamine transporter substrate/inhibitor activity of MPTP/MPP+ derivatives: a structure-activity study
(American Chemical Society, 2008-02-28)The active metabolite of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), N-methyl-4-phenylpyridinium (MPP(+)), selectively destroys the dopaminergic neurons and induces the symptoms of Parkinson's disease. Inhibition ... -
Vesicular monoamine transporters: structure-function, pharmacology, and medicinal chemistry
(John Wiley and Sons, 2011-07-01)Vesicular monoamine transporters (VMAT) are responsible for the uptake of cytosolic monoamines into synaptic vesicles in monoaminergic neurons. Two closely related VMATs with distinct pharmacological properties and tissue ... -
Viral and fungal inhibitors
(United States Patent and Trademark Office, 2013-08-20)Novel classes of viral and fungal inhibitors are disclosed. These compounds are useful in treating, preventing, and/or ameliorating viral infections such as, for example, Hepatitis C Virus, West Nile Virus, Dengue Virus, ... -
Water Soluble Porphyrin based Solar Cell
(Wichita State University. Graduate School, 2011-05-04)Porphyrins are organic chromophores with structure very close to naturally occurring pigment in leaves Chlorophyll. In addition, blood cells are red due to iron porphyrins. These versatile porphyrins are simple to synthesize ... -
What does that molecule look like? Using tandem mass spectrometry, computational chemistry and vibrational spectroscopy to determine molecular structure
(Wichita State University. Graduate School, 2009-05-01)Scientists wanting to determine the structure of a molecule have many tools at their disposal. Tandem mass spectrometry (MS/MS) allows one to study the fragmentation pathways of molecules, examining how a molecule will ... -
X-ray snapshot of the mechanism of inactivation of human neutrophil elastase by 1,2,5-thiadiazolidin-3-one 1,1-dioxide derivatives
(American Chemical Society, 2008-04-10)The mechanism of action of a general class of mechanism-based inhibitors of serine proteases, including human neutrophil elastase (HNE), has been elucidated by determining the X-ray crystal structure of an enzyme-inhibitor ...