Browsing Chemistry by Title
Now showing items 572-591 of 601
-
Tautomeric stabilities of 4-fluorohistidine shed new light on mechanistic experiments with labeled ribonuclease A
(Elsevier B.V., 2016-12-01)Ribonuclease A is the oldest model for studying enzymatic mechanisms, yet questions remain about proton transfer within the active site. Seminal work by Jackson et al. (1994) labeled Ribonuclease A with 4-fluorohistidine, ... -
Thallium(I) complexes of cyano-substituted bispyrazolylborate ligands
(Springer, 2012-07)Two thallium scorpionate complexes: dihydrobis(3-phenyl-4-cyanopyrazolyl)boratothallium(I) (TlBp(Ph,4CN)), C20H14BN6Tl and dihydrobis(3-tert-butyl-4-cyanopyrazolyl)boratothallium(I) (TlBp (t-Bu,4CN)), C16H22BN6Tl have been ... -
The development of methods to separate and identify variant lipid isomers, utilizing FAIMS and other technologies
(Wichita State University, 2018-05)The development of lipidomics has accelerated over the last decade. However, one of the major sticking points for true identification of individual lipids is the existence of isomers. Due to the complex range of possible ... -
The role of the 90 kDa palladin in the regulation of actin filaments
(Wichita State University, 2020-05)Metastasis is the most clinically significant step in cancer progression. Migration and metastasis are not fully understood, but it is clear that the actin cytoskeleton plays an essential role. Palladin is specifically ... -
Thermal switch using controlled capillary transition in heterogeneous nanostructures
(Elsevier, 2018-06)The development of a nanoscale thermal switch is a crucial step toward advanced thermal management systems including future thermal logic gates and computers. This study demonstrates a new nanoscale thermal switch mechanism ... -
Through-bond photoinduced electron transfer in a porphyrin-fullerene conjugate held by a Hamilton type hydrogen bonding motif
(The Royal Society of Chemistry, 2009-03-21)Control over the occurrence of through-bond electron transfer in self-assembled donor-acceptor conjugates is often difficult, since through-space electron transfer also competes due to the flexible nature of the spacer ... -
Time-dependent density functional theory study of the spectroscopic properties related to aggregation in the platinum(II) biphenyl dicarbonyl complex
(American Chemical Society, 2003-12-01)Singlet ground-state geometry optimization of the monomer, four dimers, and the trimer of [Pt(bph)(CO)(2)], where bph = biphenyl dianion, was performed at the B3LYP level of density functional theory (DFT) with a mixed ... -
To keep or not to keep? the question of crystallographic waters for enzyme simulations in organic solvent
(Taylor & Francis Group, 2016)The use of enzymes in non-aqueous solvents expands the use of biocatalysts to hydrophobic substrates, with the ability to tune selectivity of reactions through solvent selection. Non-aqueous enzymology also allows for ... -
Transport of tryptophan into SH-SY5Y neuronal cells
(Wichita State University. Graduate School., 2008-04-25)The human neuroblastoma cell line SH-SY5Y is a commonly used catecholaminergic model in studies related to neurotoxicity of various substances, oxidative stress, and neurodegenerative diseases. Specific transport of ... -
Tridentate N(2)S ligand from 2,2'-dithiodibenzaldehyde and N,N-dimethylethylenediamine: synthesis, structure, and characterization of a Ni(II) complex with relevance to Ni Superoxide Dismutase
(Elsevier, 2011-07-15)Nickel Superoxide Dismutase (NiSOD) and the A-cluster of Carbon Monoxide Dehydrogenase/Acetyl Coenzyme A Synthase (CODH/ACS) both feature active sites with Ni coordinated by thiolate and amide donors. It is likely that the ... -
Tuning cationic micelle properties with an antioxidant additive: A molecular perspective
(American Chemical Society, 2021-04-01)In this work, we characterize the micellization and morphology transition induced in aqueous cetyltrimethylammonium bromide (CTAB) solution by the addition of the antioxidant propyl gallate (PG) using tensiometry, rheology, ... -
Two similar dibenzo cyclic ethers with dissimilar conformations
(Wiley-Blackwell, 2009-01-01)Two dibenzo cyclic ether compounds, 6,12-dibromodibenzo[d,i]-1,2,3,6,7,8-hexahydro-1,3-dioxecin (systematic name: 8,16-dibromo-2,4-dioxatricyclo[12.4.0.0(5,10)]octadeca-5,7,9,14,16,18-hexaene), C(16)H(14)Br(2)O(2), (II), ... -
Two-component polymer films of palladium and fullerene with covalently linked crown ether voids: effect of cation binding on the redox behavior
(Springer, 2012-01)Redox active films have been generated via electrochemical reduction in a solution containing palladium(II) acetate and fulleropyrrolidine with covalently linked crown ethers, viz., benzo-15-crown-5 and benzo-18-crown-6. ... -
Ultrafast photoinduced energy and electron transfer in multi-modular donor-acceptor conjugates
(Wiley-Blackwell, 2012-10)New multi-modular donoracceptor conjugates featuring zinc porphyrin (ZnP), catechol-chelated boron dipyrrin (BDP), triphenylamine (TPA) and fullerene (C60), or naphthalenediimide (NDI) have been newly designed and synthesized ... -
Ultrafast singlet-singlet energy transfer in self-assembled via metal-ligand axial coordination of free-base porphyrin-zinc phthalocyanine and free-base porphyrin-zinc naphthalocyanine dyads
(American Chemical Society, 2010-01-14)Singlet-singlet energy transfer in self-assembled via axial coordination of imidazole-appended (at different positions of one of the meso-phenyl entities) free-base tetraphenylporphyrin, H(2)PIm, to either zinc phthalocyanine, ... -
Ultrahigh-resolution differential ion mobility separations of conformers for proteins above 10 kDa: onset of dipole alignment?
(American Chemical Society, 2014-11-04)Biomacromolecules tend to assume numerous structures in solution or the gas phase. It has been possible to resolve disparate conformational families but not unique geometries within each, and drastic peak broadening has ... -
Understanding fluorine chemical shifts and the molecular properties of organic molecules
(Wichita State University, 2018-05)Fluorinated molecules have emerged as important probes in drug design, and as strategies for enhancing protein stability and altering physicochemical properties of biological systems. Fluorine NMR plays a crucial role ... -
Urethane methacrylate reactive diluents for UV-curable polyester powder coatings
(Springer, 2021-01-15)Three urethane methacrylates, one monofunctional derivative and two di-functional derivatives with different chain lengths were used as reactive diluents in UV-curable polyester powder coatings. Each reactive diluent was ... -
Use of the 1,2,5-thiadiazolidin-3-one 1,1 dioxide and isothiazolidin-3-one 1,1 dioxide scaffolds in the design of potent inhibitors of serine proteinases
(Elsevier, 1998-03-03)The attachment of a phosphate leaving group to the 1,2,5-thiadiazolidin-3-one 1,1 dioxide and isothiazolidin-3-one 1,1 dioxide scaffolds was found to yield highly potent, time-dependent inhibitors of human leukocyte elastase ... -
Using ion mobility spectrometry to resolve isotopomers, identify isomers by isotopologic shifts, and predict mobility changes for post-translationally modified peptides
(Wichita State University, 2017-05)Differential or field asymmetric waveform ion mobility spectrometry (FAIMS) operating at high electric fields fully resolves isotopic isomers for a peptide with labeled residues. The naturally present isotopes, alone and ...