Browsing Chemistry and Biochemistry by Title
Now showing items 263-282 of 691
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The Gabriel-Colman rearrangement in biological systems: design, synthesis and biological evaluation of phthalimide and saccharin derivatives as potential mechanism-based inhibitors of human leukocyte elastase, cathepsin G and proteinase 3
(Elsevier, 1995-02-01)The results of a structure-activity relationship study focusing on the interaction of a series of phthalimide and saccharin derivatives with leukocyte elastase, cathepsin G and proteinase 3 are described. The phthalimide ... -
Gas phase attachment of water and methanol to Ag(I) complexes with alpha-amino acids in an ion trap mass spectrometer
(John Wiley and Sons, 2001-01-01)Electrospray ionization was used to generate gas phase complexes of Ag+ with selected alpha-amino acids. Following storage (isolation without collisional activation) in an ion trap mass spectrometer, the mass spectra ... -
The gas-phase bis-uranyl nitrate complex [(UO(2))(2)(NO(3))(5)](-): Infrared spectrum and structure
(Elsevier, 2011-12-01)The infrared spectrum of the bis-uranyl nitrate complex [(UO(2))(2)(NO(3))(5)](-) was measured in the gas phase using multiple photon dissociation (IRMPD). Intense absorptions corresponding to the nitrate symmetric and ... -
Gas-phase coordination complexes of (UO22+)-O-VI, (NpO22+)-O-VI, and (PuO22+)-O-VI with dimethylformamide
(Springer, 2011-11)Electrospray ionization of actinyl perchlorate solutions in H2O with 5% by volume of dimethylformamide (DMF) produced the isolatable gas-phase complexes, [An(VI)O(2)(DMF)(3)(H2O)](2+) and [An(VI)O(2)(DMF)(4)](2+), where ... -
Gas-phase H2O and O2 addition to UO2 + complexes containing single nitrile, ketone or amide ligands
(Wichita State University. Graduate School., 2006-04-28) -
Gas-phase investigation of Pd(II)-alanine complexes with small native and derivatized peptides containing histidine
(John Wiley and Sons, 2003-09-01)We report here the generation of gas-phase complexes containing Pd(II), a ligand (deprotonated alanine, A-), and/or N-terminus derivatized peptides containing histidine as one of the amino acids. The species were produced ... -
Gas-phase uranyl-nitrile complex ions
(American Chemical Society, 2006-01-26)Electrospray ionization was used to generate doubly charged complex ions composed of the uranyl ion and nitrile ligands. The complexes, with general formula [UO2(RCN)n]2+, n = 0-5 (where R=CH3-, CH3CH2-, or C6H5-), were ... -
Gene expression-based screen for Parkinson's disease identifies GW8510 as a neuroprotective agent
(American Chemical Society, 2016-07)We carried out a gene expression-based in silico screen in order to identify small molecules with gene-expression profiles that are anticorrelated with a gene-expression profile for Parkinson's disease (PD). We identified ... -
A general progress curve method for the kinetic analysis of suicide enzyme inhibitors
(Elsevier, 1996-02-15)The efficiency of suicide inhibitors is expressed in terms of the kinetic parameters KI and kinact and the partition ratio, which are commonly determined by the well-known dilution assay method. Progress curve analysis ... -
Generation and collision-induced dissociation of ammonium tetrafluoroborate cluster ions
(John Wiley and Sons, 2008-07-01)Singly and doubly charged cluster ions of ammonium tetrafluoroborate (NH4BF4) with general formula [(NH4BF4)nNH4]+ and [(NH4BF4)m(NH4)2]2+, respectively, were generated by electrospray ionization (ESI) and their fragmentation ... -
Generation of a protein based fluorescent reactive oxygen species sensor
(Wichita State University. Graduate School., 2007-04-27)The long- term goal of the project is to develop an environmentally safe, sensitive method for the detection of reactive oxygen species. The current hypothesis is that the biosynthetic incorporation of [2,5-H2]-phenylalanine ... -
Generation of gas-phase VO2+, VOOH+, and VO2+-nitrile complex ions by electrospray ionization and collision-induced dissociation
(American Chemical Society, 2006-10-19)Cationic metal species normally function as Lewis acids, accepting electron density from bound electron-donating ligands, but they can be induced to function as electron donors relative to dioxygen by careful control of ... -
Harvesting solar energy via artificial photosynthesis
(Wichita State University. Graduate School, 2010-04-23)Photosynthesis, the process of converting light energy into chemical energy, involves two major steps, absorption and transportation of light energy of appropriate wavelength by the antenna light harvesting molecules to ... -
Heteroanionic $LaBrVIO_{4}$ (VI = Mo, W): Excellence in Both Nonlinear Optical Properties and Photoluminescent Properties
(American Chemical Society, 2023-08)Five heteroanionic oxybromides, $LaBrMoO_{4}$, $LaBrWO_{4}$, $(La_{0.9}Sm_{0.1})BrMoO_{4}$, $(La_{0.9}Sm_{0.1})BrWO_{4}$, and $(La_{0.9}Dy_{0.1})BrWO_{4}$, were grown by a high-temperature salt flux method. Millimeter-sized ... -
Heterogeneous solvation shell dynamics around candida antarctica lipase b enzyme using molecular dynamics simulations: relationships with solvent structure, enzyme structure and enzyme dynamics
(Wichita State University, 2017-12)Solvent-compatible enzymes (those that function in organic solvents) are an important field of research. Understanding the relationship between solvent dynamics and protein dynamics will improve applications of proteins ... -
High-Definition Differential Ion Mobility Spectrometry with Structural Isotopic Shifts for Anionic Compounds
(American Chemical Society, 2023-07-05)Differential ion mobility spectrometry (FAIMS) had emerged in the 2000s as a novel tool for postionization separations in conjunction with mass spectrometry (MS). High-definition FAIMS introduced a decade ago has enabled ... -
High-definition ion mobility/mass spectrometry with structural isotopic shifts for nominally isobaric isotopologues
(American Chemical Society, 2023-05-04)We had reported the isotopic envelopes in differential IMS (FAIMS) separations depending on the ion structure. However, this new approach to distinguish isomers was constrained by the unit-mass resolution commingling all ... -
High-performance liquid chromatographic analysis of DNA composition and DNA modification by chloroacetaldehyde
(Elsevier, 1988-12-23)The separation of common and modified deoxyribonucleosides derived from DNA hydrolyzates was examined under different chromatographic conditions on silica-based octadecyl (C18) columns, involving hydrophobic interactions ... -
High-precision megahertz-to-terahertz dielectric spectroscopy of protein collective motions and hydration dynamics
(American Chemical Society, 2018-06-01)The low-frequency collective vibrational modes in proteins as well as the protein-water interface have been suggested as dominant factors controlling the efficiency of biochemical reactions and biological energy transport. ... -
High-resolution differential ion mobility separations/orbitrap mass spectrometry without buffer gas limitations
(American Chemical Society, 2019-04-29)Strong orthogonality between differential ion mobility spectrometry (FAIMS) and mass spectrometry (MS) makes their hybrid a powerful approach to separate isomers and isobars. Harnessing that power depends on high resolution ...