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    Structural and stability studies on domain IV of anthrax toxin protective antigen (PA); its role in anthrax pathogenesis

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    dissertation (19.89Mb)
    Date
    2018-05
    Author
    Mamillapalli, Sireesha
    Advisor
    Bann, James G.
    Metadata
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    Table of Contents
    1:Introduction -- 2: Long-range stabilization of anthrax protective antigen upon binding to CMG2 -- 3: Stability of domain IV of the anthrax toxin protective antigen and the effect of the VWA domain of CMG2 on stability -- 4: Design of a chimera of FIP-Fve and domain IV of protective antigen (PAD4) to enhance the stability of domain IV -- 5: Analysis of the immunogenicity of anthrax toxin protective antigen (PA) bound to the soluble VWA domain of CMG2 -- References -- List of figures.
    Description
    Thesis (Ph.D.)-- Wichita State University, College of Liberal Arts and Sciences, Dept. of Chemistry
    URI
    http://hdl.handle.net/10057/15418
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