Structural and stability studies on domain IV of anthrax toxin protective antigen (PA); its role in anthrax pathogenesis
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Issue Date
2018-05
Embargo End Date
Authors
Mamillapalli, Sireesha
Advisor
Bann, James G.
Citation
Abstract
Table of Content
1:Introduction -- 2: Long-range stabilization of anthrax protective antigen upon binding to CMG2 -- 3: Stability of domain IV of the anthrax toxin protective antigen and the effect of the VWA
domain of CMG2 on stability -- 4: Design of a chimera of FIP-Fve and domain IV of protective antigen (PAD4) to enhance the
stability of domain IV -- 5: Analysis of the immunogenicity of anthrax toxin protective antigen (PA) bound to the soluble
VWA domain of CMG2 -- References -- List of figures.
Description
Thesis (Ph.D.)-- Wichita State University, College of Liberal Arts and Sciences, Dept. of Chemistry