1:Introduction -- 2: Long-range stabilization of anthrax protective antigen upon binding to CMG2 -- 3: Stability of domain IV of the anthrax toxin protective antigen and the effect of the VWA domain of CMG2 on stability -- 4: Design of a chimera of FIP-Fve and domain IV of protective antigen (PAD4) to enhance the stability of domain IV -- 5: Analysis of the immunogenicity of anthrax toxin protective antigen (PA) bound to the soluble VWA domain of CMG2 -- References -- List of figures.

Thesis (Ph.D.)-- Wichita State University, College of Liberal Arts and Sciences, Dept. of Chemistry