The repository is currently being upgraded to DSpace 7. Temporarily, only admins can login. Submission of items and changes to existing items is prohibited until the completion of this upgrade process.
Insight into Ligand Binding and Conformational Dynamics of Kynurenine 3-Monooxygenase
Verma, Rajni et al. Insight into Ligand Binding and Conformational Dynamics of Kynurenine 3-Monooxygenase. Biophysical Journal , Volume 114 , Issue 3 , 570a - 571a
Cellular and developmental pathogenesis is the result of complicated cellular processes involving molecular interactions among cells and their intra- and inter-cellular milieus. The characterization of molecular interactions in different steps of disease-related metabolic pathways is necessary to understand how abnormalities in these interactions relate to disease and disorders, and how to develop therapeutic strategies to overcome these abnormalities. We focus on kynurenine 3-monooxygenase (KMO) of the kynurenine pathway, which is a metabolic pathway leading to the production of nicotinamide adenine dinucleotide from the degradation of tryptophan.
Click on the URL to access the article (may not be free).