Browsing BIO Faculty Scholarship by Subject "Mass spectrometry"

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Human FSH glycoform α-Subunit asparagine$^{52}$ glycans: Major glycan structural consistency, minor glycan variation in abundance

Butnev, Viktor Y.; May, Jeffrey V.; Brown, Alan R.; Sharma, Tarak; Butnev, Vladimir Y.; White, William K.; Harvey, David J.; Bousfield, George R. (Frontiers Media S.A., 2022-10-18)

Follicle-stimulating hormone (FSH), an α/β heterodimeric glycoprotein hormone, consists of functionally significant variants resulting from the presence or absence of either one of two FSHβ subunit N-glycans. The two most ...
Production, purification, and characterization of recombinant hFSH glycoforms for functional studies

Butnev, Viktor Y.; Butnev, Vladimir Y.; May, Jeffrey V.; Shuai, Bin; Tran, Patrick; White, William K.; Brown, Alan; Hall, Aaron Smalter; Harvey, David J.; Bousfield, George R. (Elsevier Ireland Ltd., 2015-04-15)

Previously, our laboratory demonstrated the existence of a beta-subunit glycosylation-deficient human FSH glycoform, hFSH(21). A third variant, hFSH(18), has recently been detected in FSH glycoforms isolated from purified ...