Browsing BIO Faculty Scholarship by Subject "Male"
Now showing items 1-16 of 16
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Adenosine modulation of dynorphin B release by hippocampal synaptosomes
(ElsevierElsevier BV, 1992-04-17)A rat hippocampal preparation enriched in mossy fiber synaptosomes was employed in an attempt to expose any relationship between endogenous adenosine and the release of dynorphin B-like immunoreactivity (DynB-LI). Presumptive ... -
Characterization of human FSH isoforms reveals a nonglycosylated beta-subunit in addition to the conventional glycosylated beta-subunit
(The Endocrine Society, 2001-08)Human FSH consists of a mixture of isoforms that can be separated on the basis of differences in negative charge conferred by variations in the numbers of sialic acid residues that terminate oligosaccharide branches. Western ... -
Characterization of the mouse phenylalanine hydroxylase mutation Pah(enu3)
(Academic Press, 2001-01)Phenylketonuria (PKU) is an inborn error of metabolism that is inherited in an autosomal recessive manner. It arises from a deficiency of phenylalanine hydroxylase, which is responsible for converting phenylalanine to ... -
Developing a laboratory animal model for perinatal endocrine disruption: the hamster chronicles
(Royal Society of Medicine Press Ltd., 2002-10)At the biomedical, regulatory, and public level, considerable concern surrounds the concept that inappropriate exposure to endocrine-disrupting chemicals, especially during the prenatal and/or neonatal period, may disrupt ... -
Differential progression of neonatal diethylstilbestrol-induced disruption of the hamster testis and seminal vesicle
(Elsevier, 2006-04)The synthetic estrogen diethylstilbestrol (DES) is now recognized as the prototypical endocrine disruptor. Using a hamster experimental system, we performed a detailed temporal assessment of how neonatal DES-induced ... -
Effect of maternal blood phenylalanine level on mouse maternal phenylketonuria offspring
(Academic Press, 2001-12)The genetic mouse model BTBR-Pah(enu2) was used to more thoroughly investigate the pathogenesis of maternal phenylketonuria (MPKU). More specifically, it was used to examine the effect of maternal blood phenylalanine (PHE) ... -
Endometrial hyperplasia and apoptosis following neonatal diethylstilbestrol exposure and subsequent estrogen stimulation in both host and transplanted hamster uteri
(American Association for Cancer Research, 1997-05-15)Prenatal exposure to the synthetic estrogen diethylstilbestrol (DES) causes morphogenetic alterations and neoplasia in the human reproductive tract. In the hamster, neonatal DES exposure alters early uterine morphogenesis ... -
ENU mutagenesis in the mouse
(John Wiley & Sons, 2004-02)This unit describes the treatment of laboratory mice with the mutagen N-ethyl-N-nitrosourea (ENU) to achieve very highly induced rates of mutation throughout the genome. Further, it describes several popular mating schemes ... -
Experimental histoplasmosis in the mouse. Immunoglobulin class response, total immunoglobulin A levels, immune complex formation, and occurrence of antigen in serum and urine
(American Thoracic Society, 1989-10)Biotin-avidin enzyme-linked immunosorbent assays (ELISA) were developed to study the appearance of free antibody of the IgM, G, and A classes of immune complexes (IC) containing those classes and of antigen in the serum ... -
Feeding evoked by electrical stimulation in collared lizards
(Elsevier, 1988)Feeding was evoked in collared lizards, Crotaphytus collaris, using electrical stimulation of the brain (ESB). Stimulation sites were tested in the forebrain and midbrain of 39 animals. Six stimulation loci were localized ... -
Identification of twelve O-glycosylation sites in equine chorionic gonadotropin beta and equine luteinizing hormone ss by solid-phase Edman degradation
(Society for the Study of Reproduction, 2001-01)The O-glycosylation sites for equine LHss (eLHss) and eCGss were identified by solid-phase Edman degradation of four glycopeptides derived from the C-terminal region. Both subunits were O-glycosylated at the same 12 ... -
Increased urotensin I and II immunoreactivity in the urophysis of Gillichthys mirabilis transferred to low salinity water
(Academic Press, 1991-09)The function of the fish caudal neurosecretory system is uncertain, but a role in osmoregulation has been suggested by many investigators. Our objective was to determine if acclimation to water of different salinity has ... -
Inositol phosphate stimulation by LH requires the entire alpha Asn56 oligosaccharide
(Elsevier Ireland Ltd, 2003-01-31)Lentil lectin-bound, fucose-enriched hTSH was reported to stimulate both cAMP and inositol phosphate (IP) intracellular signalling pathways, whereas fucose-depleted hTSH stimulated only the cAMP pathway. Gonadotropins ... -
Linkage analysis of the hph-1 mutation and the GTP cyclohydrolase I structural gene
(Academic Press, 1999-09)Our research establishes genetic linkage between the hph-1 mutation and the GTP-CH I structural gene. Our results indicate that these two loci are within an 8 cM region with 95% confidence. This finding lends additional ... -
Negative influence of O-linked oligosaccharides of high molecular weight equine chorionic gonadotropin on its luteinizing hormone and follicle-stimulating hormone receptor-binding activities
(The Endocrine Society, 1996-06)Three equine CG (eCG) forms with identical amino acid sequences but different mol wt and monosaccharide compositions were isolated from a crude eCG preparation and designated eCG-L (low mol wt), eCG-M (medium mol wt), and ... -
Postnatal growth in a mouse genetic model of classical phenylketonuria
(American Association for Laboratory Animal Science, 2000-11)Because of the ethical problems of withholding dietary treatment from patients with phenylketonuria, effectively studying long-term effects such as postnatal growth rates is difficult or impossible. The only literature ...